Treatment strategies for cryptococcal infection: challenges, advances and future outlook
Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …
The pathobiology of human fungal infections
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …
Neuroinfections caused by fungi
K Góralska, J Blaszkowska, M Dzikowiec - Infection, 2018 - Springer
Background Fungal infections of the central nervous system (FIs-CNS) have become
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …
significantly more common over the past 2 decades. Invasion of the CNS largely depends on …
Combatting the evolution of antifungal resistance in Cryptococcus neoformans
A Bermas, J Geddes‐McAlister - Molecular microbiology, 2020 - Wiley Online Library
Fungal infections are a global concern and the evolution of intrinsic resistance to current
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
antifungals presents an alarming problem. For Cryptococcus neoformans, a human fungal …
Race and ethnicity: Risk factors for fungal infections?
Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …
Cryptococcosis in solid organ transplantation—guidelines from the American Society of Transplantation Infectious Diseases Community of Practice
JW Baddley, GN Forrest… - Clinical …, 2019 - Wiley Online Library
These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …
American Society of Transplantation review the diagnosis, prevention, and management of …
The status of cryptococcosis in Latin America
C Firacative, J Lizarazo, MT Illnait-Zaragozí… - Memórias do Instituto …, 2018 - SciELO Brasil
Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …
Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as …
Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection
YN Li, ZW Wang, F Li, LH Zhou, YS Jiang, Y Yu… - Nature …, 2022 - nature.com
Cryptococcosis is a potentially lethal disease that is primarily caused by the fungus
Cryptococcus neoformans, treatment options for cryptococcosis are limited. Here, we show …
Cryptococcus neoformans, treatment options for cryptococcosis are limited. Here, we show …
The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis
IM Dambuza, T Drake, A Chapuis, X Zhou… - PLoS …, 2018 - journals.plos.org
Fungal cells change shape in response to environmental stimuli, and these morphogenic
transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch …
transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch …
Advances in the diagnosis and treatment of fungal infections of the CNS
Fungal infections of the CNS are challenging to treat and their optimal management requires
knowledge of their epidemiology, host characteristics, diagnostic criteria, and therapeutic …
knowledge of their epidemiology, host characteristics, diagnostic criteria, and therapeutic …