Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Surface-based morphometry (SBM) is extremely useful for estimating the indices of cortical
morphology, such as volume, thickness, area, and gyrification, whereas voxel-based …

Radiological images have been assessed qualitatively in most clinical settings by the expert
eyes of radiologists and other clinicians. On the other hand, quantification of radiological …

Magnetization transfer (MT) imaging has been widely used for estimating myelin content in
the brain. Recently, two other approaches, namely simultaneous tissue relaxometry of R1 …

Magnetic resonance imaging (MRI) is the gold standard imaging technique for diagnosis
and monitoring of many neurological diseases. However, the application of conventional …

Objectives The aim of this study was to evaluate the linearity, bias, intrascanner
repeatability, and interscanner reproducibility of quantitative values derived from a …

Background Previous methods for the quantification of brain tissue properties by magnetic
resonance imaging were mainly based on two-dimensional acquisitions and were thus …

Background: Paramagnetic rim lesions (PRLs) are an imaging biomarker in multiple
sclerosis (MS), associated with a more severe disease. Objectives: To determine …

Background The histological grade of bladder cancer (BCa) is an important factor
associated with the treatment and prognosis. However, accurate determination of the …

One major thrust in radiology today is image standardization with a focus on rapidly
acquired quantitative multi-contrast information. This is critical for multi-center trials, for the …