Surface interaction at the biomaterial–cell interface is essential for a variety of cellular
functions, such as adhesion, proliferation, and differentiation. Nevertheless, changes in the …

Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

Cartilage is frequently damaged with a limited capacity for repair. Current treatment
strategies are insufficient as they form fibrocartilage as opposed to hyaline cartilage, and do …

Articular cartilage is composed of chondrons within a territorial matrix surrounded by a
highly organized extracellular matrix comprising collagen II fibrils, proteoglycans …

Over the past two decades, evidence has emerged for the existence of a distinct population
of endogenous progenitor cells in adult articular cartilage, predominantly referred to as …

Osteoarthritis, the most prevalent form of joint disease, afflicts 9% of the US population over
the age of 30 and costs the economy nearly $100 billion annually in healthcare and …

Nasal cartilage pathologies are common; for example, up to 80% of people are afflicted by
deviated nasal septum conditions. Because cartilage provides the supportive framework of …

Maintenance of tissue homeostasis and tissue regeneration after an insult are essential
functions of adult stem cells (SCs). In adult tissues, SCs proliferate at a very slow rate within …

Objective Meniscus injuries in the inner avascular zone have weak intrinsic self-healing
capacity and often progress to osteoarthritis. This study focused on evaluating the effects of …

Meniscus cartilage has poor self-healing capacity in the inner zone and its damage leads to
articular cartilage degeneration. Here we have developed hybrid constructs using …