The evolution of Staphylococcus aureus during the modern antibiotic era has been
delineated by distinct strain emergence events, many of which include acquisition of …

The polymyxin and lipopeptide classes of antibiotics are membrane-targeting drugs of last
resort used to treat infections caused by multi-drug-resistant pathogens. Despite similar …

The emergence of vancomycin-intermediate Staphylococcus aureus (VISA) and
heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) over the past …

Gram‐positive bacteria possess a permeable cell wall that usually does not restrict the
penetration of antimicrobials. However, resistance due to restricted penetration can occur …

The emergence of mutations in nucleic acids is one of the major factors underlying
evolution, providing the working material for natural selection. Most bacteria are haploid for …

Background. Vancomycin treatment failure in methicillin-resistant Staphylococcus aureus
(MRSA) bacteremia is not uncommon, even when MRSA is susceptible to vancomycin. The …

Photodynamic therapy (PDT) appears to be endowed with several favourable features for
the treatment of localized microbial infections, especially after the advent of cationic …

Strains of Staphylococcus aureus with reduced susceptibility to glycopeptides have been
reported from Japan, the United States, Europe, and the Far East. Although isolates with …

Staphylococcus epidermidis, the most frequently isolated coagulase‐negative
staphylococcus, is the leading cause of infection related to implanted medical devices …

The sensitivity and specificity of seven methods (agar dilution, broth microdilution, Etest at
0.5 and 2.0 McFarland (McF) inocula, two agar screening methods, and population studies …