Heart failure (HF) is a systemic illness with grave implications for bodily functions. The brain,
among other vital organs, often suffers insults as a result of HF, and both anatomic and …

The use of cardiopulmonary bypass (CPB) in cardiac surgery has often been associated
with postoperative organ dysfunction. Roller and centrifugal pumps produce non-pulsatile …

BACKGROUND: Controversy exists regarding the optimal perfusion modality during
cardiopulmonary bypass (CPB). Here we compare the effects of pulsatile versus …

The onset of nonpulsatile cardiopulmonary bypass is known to deteriorate microcirculatory
perfusion, but it has never been investigated whether this may be prevented by restoration of …

Background Pulsatile perfusion may offer microcirculatory advantages over conventional
nonpulsatile perfusion during cardiopulmonary bypass (CPB). Here, we present direct visual …

Variability in arterial pressure and cerebral blood flow has traditionally been interpreted as a
marker of cardiovascular decompensation, and has been associated with negative clinical …

Multiple studies have evaluated the efficacy of pulsatile flow during cardiopulmonary bypass
(CPB) showing controversial results. Suggested benefits to pulsatile perfusion include …

Background There is increasing recognition that the risk of stroke after left ventricular assist
device (LVAD) implantation varies based on gender, with a higher risk in female patients …

Background Insertion of a left ventricular assist device (LVAD) is an accepted therapy for
advanced heart failure patients. However, the effects on end-organ perfusion, including …

Background: The role of pulsatile (PP) versus non-pulsatile (NP) flow during a
cardiopulmonary bypass (CPB) is still debated. This study's aim was to analyze …