Magnetization transfer contrast and chemical exchange saturation transfer MRI. Features and analysis of the field-dependent saturation spectrum

PCM Van Zijl, WW Lam, J Xu, L Knutsson, GJ Stanisz - Neuroimage, 2018 - Elsevier
Abstract Magnetization Transfer Contrast (MTC) and Chemical Exchange Saturation
Transfer (CEST) experiments measure the transfer of magnetization from molecular protons …

An overview of CEST MRI for non-MR physicists

B Wu, G Warnock, M Zaiss, C Lin, M Chen, Z Zhou… - EJNMMI physics, 2016 - Springer
The search for novel image contrasts has been a major driving force in the magnetic
resonance (MR) research community, in order to gain further information on the body's …

Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging

O Ciccarelli, F Barkhof, B Bodini, N De Stefano… - The Lancet …, 2014 - thelancet.com
The mechanisms underlying the pathogenesis of multiple sclerosis induce the changes that
underpin relapse-associated and progressive disability. Disease mechanisms can be …

Chemical exchange saturation transfer (CEST) and MR Z-spectroscopy in vivo: a review of theoretical approaches and methods

M Zaiss, P Bachert - Physics in Medicine & Biology, 2013 - iopscience.iop.org
Chemical exchange saturation transfer (CEST) of metabolite protons that undergo exchange
processes with the abundant water pool enables a specific contrast for magnetic resonance …

Chemical exchange saturation transfer (CEST) imaging: description of technique and potential clinical applications

F Kogan, H Hariharan, R Reddy - Current radiology reports, 2013 - Springer
Chemical exchange saturation transfer (CEST) is a magnetic resonance imaging (MRI)
contrast enhancement technique that enables indirect detection of metabolites with …

In vivo Imaging of Glial Activation in Alzheimer's Disease

P Edison, CK Donat, M Sastre - Frontiers in neurology, 2018 - frontiersin.org
Alzheimer's disease (AD) is characterized by memory loss and decline of cognitive function,
associated with progressive neurodegeneration. While neuropathological processes like …

Creatine and phosphocreatine map** of mouse skeletal muscle by a polynomial and Lorentzian line‐shape fitting CEST method

L Chen, PB Barker, RG Weiss… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose To obtain high‐resolution Cr and PCr maps of mouse skeletal muscle using a
polynomial and Lorentzian line‐shape fitting (PLOF) CEST method. Methods Wild‐type mice …

Chemical exchange saturation transfer imaging of creatine, phosphocreatine, and protein arginine residue in tissues

J Xu, JJ Chung, T ** - NMR in Biomedicine, 2023 - Wiley Online Library
Chemical exchange saturation transfer (CEST) MRI has become a promising technique to
assay target proteins and metabolites through their exchangeable protons, noninvasively …

[HTML][HTML] Label-free CEST MRI detection of citicoline-liposome drug delivery in ischemic stroke

H Liu, A Jablonska, Y Li, S Cao, D Liu, H Chen… - Theranostics, 2016 - ncbi.nlm.nih.gov
Citicoline (CDPC) is a natural supplement with well-documented neuroprotective effects in
the treatment of neurodegenerative diseases. In the present study, we sought to exploit …

Salicylic acid and analogues as diaCEST MRI contrast agents with highly shifted exchangeable proton frequencies.

X Yang, X Song, Y Li, G Liu… - Angewandte …, 2013 - search.ebscohost.com
More than water: Chemical exchange saturation transfer (CEST) contrast agents have used
water bound to lanthanides as a source of highly shifted exchangeable proton frequencies …