Solid-state NMR: Methods for biological solids

S Ahlawat, KR Mote, NA Lakomek… - Chemical Reviews, 2022‏ - ACS Publications
In the last two decades, solid-state nuclear magnetic resonance (ssNMR) spectroscopy has
transformed from a spectroscopic technique investigating small molecules and industrial …

Spectroscopic methods for analysis of protein secondary structure

JT Pelton, LR McLean - Analytical biochemistry, 2000‏ - Elsevier
Several methods for determination of the secondary structure of proteins by spectroscopic
measurements are reviewed. Circular dichroism (CD) spectroscopy provides rapid …

Atomic-resolution structure of a disease-relevant Aβ (1–42) amyloid fibril

MA Wälti, F Ravotti, H Arai, CG Glabe, JS Wall… - Proceedings of the …, 2016‏ - pnas.org
Amyloid-β (Aβ) is present in humans as a 39-to 42-amino acid residue metabolic product of
the amyloid precursor protein. Although the two predominant forms, Aβ (1–40) and Aβ (1 …

BioMagResBank

EL Ulrich, H Akutsu, JF Doreleijers… - Nucleic acids …, 2007‏ - academic.oup.com
The BioMagResBank (BMRB: www. bmrb. wisc. edu) is a repository for experimental and
derived data gathered from nuclear magnetic resonance (NMR) spectroscopic studies of …

1H, 13C and 15N chemical shift referencing in biomolecular NMR

DS Wishart, CG Bigam, J Yao, F Abildgaard… - Journal of biomolecular …, 1995‏ - Springer
A considerable degree of variability exists in the way that 1 H, 13 C and 15 N chemical shifts
are reported and referenced for biomolecules. In this article we explore some of the reasons …

1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

DS Wishart, CG Bigam, A Holm, RS Hodges… - Journal of biomolecular …, 1995‏ - Springer
In this study we report on the 1 H, 13 C and 15 N NMR chemical shifts for the random coil
state and nearest-neighbor sequence effects measured from the protected linear …

Conformational coupling across the plasma membrane in activation of the EGF receptor

NF Endres, R Das, AW Smith, A Arkhipov, E Kovacs… - Cell, 2013‏ - cell.com
How the epidermal growth factor receptor (EGFR) activates is incompletely understood. The
intracellular portion of the receptor is intrinsically active in solution, and to study its …

Heteronuclear multidimensional NMR experiments for the structure determination of proteins in solution employing pulsed field gradients

M Sattler, J Schleucher, C Griesinger - Progress in nuclear magnetic …, 1999‏ - Elsevier
6. 3D and 4D NOESY/ROESY experiments............................................ 146 6.1. 13C-and 15N-
edited NOESY/ROESY experiments.................................. 146 6.2. Filtered experiments for …

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

G Cornilescu, F Delaglio, A Bax - Journal of biomolecular NMR, 1999‏ - Springer
Chemical shifts of backbone atoms in proteins are exquisitely sensitive to local
conformation, and homologous proteins show quite similar patterns of secondary chemical …

An introduction to biological NMR spectroscopy

D Marion - Molecular & Cellular Proteomics, 2013‏ - mcponline.org
NMR spectroscopy is a powerful tool for biologists interested in the structure, dynamics, and
interactions of biological macromolecules. This review aims at presenting in an accessible …