Metformin, a biological and synthetic overview

ED Hernández-Velázquez, C Alba-Betancourt… - Bioorganic & Medicinal …, 2023 - Elsevier
Metformin is the most widely known anti-hyperglycemic, officially acquired by the USA
government in 1995 and in 2001 it became the most prescribed treatment for type II …

Iodine (III)‐Aluminum or‐Ammonium Salts for the Oxidative Aromatic Inorganic Functionalization

R Chávez‐Rivera, P Navarro‐Santos… - …, 2023 - Wiley Online Library
Strategies for introducing halogens and other inorganic groups in aromatic systems, usually
involve non‐general and strong oxidative protocols which resulted in poor functional group …

Synthesis and Anti‐inflammatory Effect of Simple 2, 3‐Diarylindoles. On Route to New NSAID Scaffolds

LA Segura‐Quezada, C Alba‐Betancourt… - …, 2024 - Wiley Online Library
Nitrogen‐containing drugs represent one of the worldwide most extensive sources of
treatments for different diseases. Indomethacin as example, is one of the most important non …

Ningalins, Pyrrole‐Bearing Metabolites Isolated from Didemnum spp. Synthesis and MDR‐Reversion Activity in Cancer Therapy

LA Segura‐Quezada… - Chemistry & …, 2024 - Wiley Online Library
Abstract Multi‐Drug Resistance (MDR) is one of the most frequent problems observed in the
course of cancer chemotherapy. Cells under treatment, tend to develop survival …

Synthesis and in vivo Evaluation of Fluorobenzyl Metformin Derivatives as Potential Drugs in The Diabetes Treatment

ED Hernández‐Velázquez, MD Herrera… - Asian Journal of …, 2023 - Wiley Online Library
Metformin is a versatile, biocompatible, and cheap bis‐guanidine used as first response line
in the type II diabetes treatment. Since its first human trials (1956) several structural …

Iodine (III) reagents for the aromatic functionalization with inorganic groups

MP Barrera-Nava, LA Segura-Quezada… - Tetrahedron, 2024 - Elsevier
Iodine (III) reagents have gained importance in organic synthesis due to their strong
oxidative properties in addition to several advantages over other related such as, non-toxic …

Differential Effect of 4H-Benzo[d] [1,3]oxazines on the Proliferation of Breast Cancer Cell Lines

I Fraire-Soto, JG Araujo-Huitrado… - Current Medicinal …, 2024 - benthamdirect.com
Background A family of 4 H-benzo [d][1, 3] oxazines were obtained from a group of N-(2-
alkynyl) aryl benzamides precursors via gold (I) catalysed chemoselective 6-exo-dig CO …

Multidrug Resistance Reversed by Maleimide Interactions. A Biological and Synthetic Overview for an Emerging Field

ED Hernández‐Velázquez… - …, 2025 - Wiley Online Library
Multidrug Resistance (MDR) can be considered one of the most frightening adaptation types
in bacteria, fungi, protozoa, and eukaryotic cells. It allows the organisms to survive the attack …

[TRÍCH DẪN][C] The literature of heterocyclic chemistry, part XXII, 2022

GA Gazieva, YB Evdokimenkova, NO Soboleva - 2025 - Elsevier