[HTML][HTML] Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications
Q Kang, C Yang - Redox biology, 2020 - Elsevier
Oxidative stress, a cytopathic outcome of excessive generation of ROS and the repression of
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …
antioxidant defense system for ROS elimination, is involved in the pathogenesis of multiple …
Healthy effects of plant polyphenols: molecular mechanisms
The increasing extension in life expectancy of human beings in developed countries is
accompanied by a progressively greater rate of degenerative diseases associated with …
accompanied by a progressively greater rate of degenerative diseases associated with …
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy
medicine and medicine be thy food.” Exploring the association between diet and health …
medicine and medicine be thy food.” Exploring the association between diet and health …
Diet, lifestyle and cardiovascular diseases: linking pathophysiology to cardioprotective effects of natural bioactive compounds
Heart and blood vessels disorders comprise one of the main causes of death worldwide.
Pharmacologically active natural compounds have been used as a complementary therapy …
Pharmacologically active natural compounds have been used as a complementary therapy …
Protein lysine acetylation by p300/CBP
Since their discovery in the 1980s and 1990s, the human protein lysine acetyltransferase
encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP …
encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP …
Regulation of SIRT1 in cellular functions: role of polyphenols
S Chung, H Yao, S Caito, J Hwang… - Archives of biochemistry …, 2010 - Elsevier
Sirtuin 1 (SIRT1) is known to deacetylate histones and non-histone proteins including
transcription factors thereby regulating metabolism, stress resistance, cellular survival …
transcription factors thereby regulating metabolism, stress resistance, cellular survival …
Writers and readers of histone acetylation: structure, mechanism, and inhibition
R Marmorstein, MM Zhou - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Histone acetylation marks are written by histone acetyltransferases (HATs) and read by
bromodomains (BrDs), and less commonly by other protein modules. These proteins …
bromodomains (BrDs), and less commonly by other protein modules. These proteins …
Polyphenols in the treatment of autoimmune diseases
In addition to protecting body from infections and diseases, the immune system produces
auto-antibodies that can cause complex autoimmune disorders, such as Type I diabetes …
auto-antibodies that can cause complex autoimmune disorders, such as Type I diabetes …
Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition
Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …
prognosis of the affected patient. Genomic instability arises from many different pathways …
[HTML][HTML] Oxidative stress, mitochondrial damage and diabetic retinopathy
Diabetes has emerged as an epidemic of the 21st century, and retinopathy remains the
leading cause of blindness in young adults and the mechanism of this blinding disease …
leading cause of blindness in young adults and the mechanism of this blinding disease …