Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

The emergence of SARS-CoV-2 and subsequent COVID-19 pandemic has resulted in a
significant global public health burden, leading to an urgent need for effective therapeutic …

Monoclonal antibody (mAb) therapy has been previously exploited for viral infections, such
as respiratory syncytial virus pneumonia and Ebolavirus disease. In the ongoing COVID-19 …

The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

Camelid single-domain antibodies, also known as nanobodies, can be readily isolated from
naïve libraries for specific targets but often bind too weakly to their targets to be immediately …

The recent outbreak of SARS-CoV-2 has forever altered mankind resulting in the COVID-19
pandemic. This respiratory virus further manifests into vital organ damage, resulting in …

Tools to monitor SARS-CoV-2 transmission and immune responses are needed. We present
a neutralization ELISA to determine the levels of Ab-mediated virus neutralization and a …

The optimization of antibodies to attain the desired levels of affinity and specificity holds
great promise for the development of next generation therapeutics. This study delves into the …

Chloroquine and its derivatives have been used since ages to treat malaria and have also
been approved by the FDA to treat autoimmune diseases. The drug employs pH-dependent …

Abstract Background Since December 2019, the newly emerged SARS-CoV-2 virus
continues to infect humans and many people died from severe Covid-19 during the last 2 …