Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

Abstract The Transporter Classification Database (TCDB; http://www. tcdb. org) is a freely
accessible reference database for transport protein research, which provides structural …

INTRODUCTION Resolving the molecular details of proteome variation in the different
tissues and organs of the human body would greatly increase our knowledge of human …

Cell-surface proteins are of great biomedical importance, as demonstrated by the fact that
66% of approved human drugs listed in the DrugBank database target a cell-surface protein …

Abstract TOPCONS (http://topcons. net/) is a widely used web server for consensus
prediction of membrane protein topology. We hereby present a major update to the server …

Ever since the signal hypothesis was proposed in 1971, the exact nature of signal peptides
has been a focus point of research. The prediction of signal peptides and protein subcellular …

The GENCODE Consortium aims to identify all gene features in the human genome using a
combination of computational analysis, manual annotation, and experimental validation …

To the Editor: The secretory signal peptide is a ubiquitous proteinsorting signal that targets
its passenger protein for translocation across the endoplasmic reticulum membrane in …

Determining the full complement of protein-coding genes is a key goal of genome
annotation. The most powerful approach for confirming protein-coding potential is the …

PredictProtein is a meta-service for sequence analysis that has been predicting structural
and functional features of proteins since 1992. Queried with a protein sequence it returns …