Metabolic heterogeneity in tumor microenvironment–A novel landmark for immunotherapy

C Chen, P Han, Y Qing - Autoimmunity Reviews, 2024 - Elsevier
The surrounding non-cancer cells and tumor cells that make up the tumor microenvironment
(TME) have various metabolic rhythms. TME metabolic heterogeneity is influenced by the …

Linear Response Theory of Evolved Metabolic Systems

JF Yamagishi, TS Hatakeyama - Physical Review Letters, 2023 - APS
Predicting cellular metabolic states is a central problem in biophysics. Conventional
approaches, however, sensitively depend on the microscopic details of individual metabolic …

The role of competition versus cooperation in microbial community coalescence

P Lechón, T Clegg, J Cook, TP Smith, S Pawar - bioRxiv, 2021 - biorxiv.org
New microbial communities often arise through the mixing of two or more separately
assembled parent communities, a phenomenon that has been termed “community …

Microbiomes: human and environment

LQ Vieira - Biophysical Reviews, 2021 - Springer
We are surrounded by microorganisms. Since Anton Van Leeuwenhoek described bacteria
and life in a drop of water in 1675, we have been fascinated by these living beings. Use of …

Microbial Potlatch: Cell-level adaptation of leakiness of metabolites leads to resilient symbiosis among diverse cells

JF Yamagishi, N Saito, K Kaneko - bioRxiv, 2020 - biorxiv.org
Microbial communities display extreme diversity, facilitated by the secretion of chemicals that
can create new niches. However, it is unclear why cells often secrete even essential …