Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder

AJ Cutler, GW Mattingly, V Maletic - Translational Psychiatry, 2023 - nature.com
The pathophysiology of major depressive disorder (MDD) is thought to result from impaired
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …

Functional MRI in major depressive disorder: A review of findings, limitations, and future prospects

J Pilmeyer, W Huijbers, R Lamerichs… - Journal of …, 2022 - Wiley Online Library
Objective diagnosis and prognosis in major depressive disorder (MDD) remains a challenge
due to the absence of biomarkers based on physiological parameters or medical tests …

Altered patterns of central executive, default mode and salience network activity and connectivity are associated with current and future depression risk in two …

MA Bertocci, Y Afriyie-Agyemang, R Rozovsky… - Molecular …, 2023 - nature.com
Neural markers of pathophysiological processes underlying the dimension of subsyndromal-
syndromal-level depression severity can provide objective, biologically informed targets for …

Crosstalk between existential phenomenological psychotherapy and neurological sciences in mood and anxiety disorders

L Balogh, M Tanaka, N Török, L Vécsei, S Taguchi - Biomedicines, 2021 - mdpi.com
Psychotherapy is a comprehensive biological treatment modifying complex underlying
cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with …

[HTML][HTML] “Inflamed” depression: A review of the interactions between depression and inflammation and current anti-inflammatory strategies for depression

Y Yin, T Ju, D Zeng, F Duan, Y Zhu, J Liu, Y Li… - Pharmacological …, 2024 - Elsevier
Depression is a common mental disorder, the effective treatment of which remains a
challenging issue worldwide. The clinical pathogenesis of depression has been deeply …

Shared and distinct brain fMRI response during performance of working memory tasks in adult patients with schizophrenia and major depressive disorder

X Wang, B Cheng, N Roberts, S Wang… - Human brain …, 2021 - Wiley Online Library
Working memory (WM) impairments are common features of psychiatric disorders. A
systematic meta‐analysis was performed to determine common and disorder‐specific brain …

Understanding complex functional wiring patterns in major depressive disorder through brain functional connectome

Z Yang, L Jian, H Qiu, C Zhang, S Cheng, J Ji… - Translational …, 2021 - nature.com
Brain function relies on efficient communications between distinct brain systems. The
pathology of major depressive disorder (MDD) damages functional brain networks, resulting …

Sustained attention alterations in major depressive disorder: a review of fMRI studies employing Go/No-Go and CPT tasks

MC Piani, E Maggioni, G Delvecchio… - Journal of affective …, 2022 - Elsevier
Background Major depressive disorder (MDD) is a severe psychiatric condition
characterized by selective cognitive dysfunctions. In this regard, functional Magnetic …

How do serotonergic psychedelics treat depression: The potential role of neuroplasticity

H Artin, S Zisook, D Ramanathan - World journal of psychiatry, 2021 - pmc.ncbi.nlm.nih.gov
Depression is a common mental disorder and one of the leading causes of disability around
the world. Monoaminergic antidepressants often take weeks to months to work and are not …

[HTML][HTML] Depressive disorder recognition based on frontal EEG signals and deep learning

Y Xu, H Zhong, S Ying, W Liu, G Chen, X Luo, G Li - Sensors, 2023 - mdpi.com
Depressive disorder (DD) has become one of the most common mental diseases, seriously
endangering both the affected person's psychological and physical health. Nowadays, a DD …