Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Background Precision medicine, space exploration, drug discovery to characterization of
dark chemical space of habitats and organisms, metabolomics takes a centre stage in …

Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …

Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …

Spectral similarity is used as a proxy for structural similarity in many tandem mass
spectrometry (MS/MS) based metabolomics analyses such as library matching and …

Background Untargeted metabolomics approaches based on mass spectrometry obtain
comprehensive profiles of complex biological samples. However, on average only 10% of …

A substantial fraction of metabolic features remains undetermined in mass spectrometry
(MS)-based metabolomics, and molecular formula annotation is the starting point for …

Both targeted and untargeted mass spectrometry-based metabolomics approaches are used
to understand the metabolic processes taking place in various organisms, from prokaryotes …

Unknown forever chemicals like per-and polyfluoroalkyl substances (PFASs) are difficult to
identify. Current platforms designed for metabolites and natural products cannot capture the …

Food fraud is currently a growing global concern with far‐reaching consequences. Food
authenticity attributes, including biological identity, geographical origin, agricultural …