The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Evidence is provided for a new conceptualization of the connectivity and functions of the
cingulate cortex in emotion, action, and memory. The anterior cingulate cortex receives …

Deep reinforcement learning (RL) methods have driven impressive advances in artificial
intelligence in recent years, exceeding human performance in domains ranging from Atari to …

The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

It is proposed that a cognitive map encoding the relationships between entities in the world
supports flexible behavior, but the majority of the neural evidence for such a system comes …

" Our thoughts are meaningful. We think about things in the outside world; how can that be
so? This is one of the deepest questions in contemporary philosophy. Ever since …

The prefrontal cortex (PFC) plays a critical role in the generation and regulation of emotion.
However, we lack an integrative framework for understanding how different emotion-related …

The processing of rewards and losses are crucial to everyday functioning. Considerable
interest has been attached to investigating the anticipation and outcome phases of reward …

Corticostriatal connections play a central role in develo** appropriate goal-directed
behaviors, including the motivation and cognition to develop appropriate actions to obtain a …