A review on applications of computational methods in drug screening and design
Drug development is one of the most significant processes in the pharmaceutical industry.
Various computational methods have dramatically reduced the time and cost of drug …
Various computational methods have dramatically reduced the time and cost of drug …
[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges
I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …
targeted and effective administration. However, the intricate interplay between drug …
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
Analyses of drug pharmacokinetics (PKs) and pharmacodynamics (PDs) performed in
animals are often not predictive of drug PKs and PDs in humans, and in vitro PK and PD …
animals are often not predictive of drug PKs and PDs in humans, and in vitro PK and PD …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Targeting phospholipid metabolism in cancer
All cancers tested so far display abnormal choline and ethanolamine phospholipid
metabolism, which has been detected with numerous magnetic resonance spectroscopy …
metabolism, which has been detected with numerous magnetic resonance spectroscopy …
Omics-based strategies in precision medicine: toward a paradigm shift in inborn errors of metabolism investigations
The rise of technologies that simultaneously measure thousands of data points represents
the heart of systems biology. These technologies have had a huge impact on the discovery …
the heart of systems biology. These technologies have had a huge impact on the discovery …
Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics
N Chiamvimonvat, Y Chen‐Izu… - The Journal of …, 2017 - Wiley Online Library
This is the second of the two White Papers from the fourth UC Davis Cardiovascular
Symposium Systems Approach to Understanding Cardiac Excitation–Contraction Coupling …
Symposium Systems Approach to Understanding Cardiac Excitation–Contraction Coupling …
Bioavailability by design—Vitamin D3 liposomal delivery vehicles
P Dałek, D Drabik, H Wołczańska, A Foryś… - … , Biology and Medicine, 2022 - Elsevier
Vitamin D3 deficiency has serious health consequences, as demonstrated by its effect on
severity and recovery after COVID-19 infection. Because of high hydrophobicity, its …
severity and recovery after COVID-19 infection. Because of high hydrophobicity, its …
Mathematical and computational modeling of nano-engineered drug delivery systems
While the advent of nano-engineered drug delivery systems (DDSs) has revived hopes for
better management of a wide range of pathologies, critical appraisal of the field has shown …
better management of a wide range of pathologies, critical appraisal of the field has shown …
Revolutionizing animation: unleashing the power of artificial intelligence for cutting-edge visual effects in films
Integrating artificial intelligence (AI) technology with the cinema and television sectors has
resulted in significant transformations in the programming and production of television …
resulted in significant transformations in the programming and production of television …