Large animal models in regenerative medicine and tissue engineering: to do or not to do
I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …
increasing drive toward clinical translation of breakthrough technologies. However, the …
Equine asthma: current understanding and future directions
The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the
latest information on Equine Asthma and provide future research directions. Current clinical …
latest information on Equine Asthma and provide future research directions. Current clinical …
Equine asthma: Integrative biologic relevance of a recently proposed nomenclature
The term “equine asthma” has been proposed as a unifying descriptor of inflammatory
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
airway disease (IAD), recurrent airway obstruction (RAO), and summer pasture‐associated …
Heaves, an asthma‐like disease of horses
M Leclere, A LAVOIE‐LAMOUREUX, JP LAVOIE - Respirology, 2011 - Wiley Online Library
Animal models have been developed to investigate specific components of asthmatic airway
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
inflammation, hyper‐responsiveness or remodelling. However, all of these aspects are …
Asthma “of horses and men”—How can equine heaves help us better understand human asthma immunopathology and its functional consequences?
Animal models have been studied to unravel etiological, immunopathological, and genetic
attributes leading to asthma. However, while experiments in which the disease is artificially …
attributes leading to asthma. However, while experiments in which the disease is artificially …
An observational study of environmental exposures, airway cytology, and performance in racing thoroughbreds
KM Ivester, LL Couëtil, GE Moore - Journal of veterinary internal …, 2018 - Wiley Online Library
Background Mild equine asthma is presumed to arise in response to environmental
exposures but the relative impact of differing inflammatory phenotypes upon performance …
exposures but the relative impact of differing inflammatory phenotypes upon performance …
Structure and function of small airways in asthma patients revisited
WB van den Bosch, AL James… - European Respiratory …, 2021 - Eur Respiratory Soc
Small airways (< 2 mm in diameter) are probably involved across almost all asthma
severities and they show proportionally more structural and functional abnormalities with …
severities and they show proportionally more structural and functional abnormalities with …
The equine asthma model of airway remodeling: from a veterinary to a human perspective
Human asthma is a complex and heterogeneous disorder characterized by chronic
inflammation, bronchospasm and airway remodeling. The latter is a major determinant of the …
inflammation, bronchospasm and airway remodeling. The latter is a major determinant of the …
An official American Thoracic Society research statement: current challenges facing research and therapeutic advances in airway remodeling
Background: Airway remodeling (AR) is a prominent feature of asthma and other obstructive
lung diseases that is minimally affected by current treatments. The goals of this Official …
lung diseases that is minimally affected by current treatments. The goals of this Official …
Corticosteroids and antigen avoidance decrease airway smooth muscle mass in an equine asthma model
M Leclere, A Lavoie-Lamoureux, P Joubert… - American Journal of …, 2012 - atsjournals.org
Recent studies suggest that airway smooth muscle remodeling is an early event in the
course of asthma. Little is known of the effects of long-term antigen avoidance and inhaled …
course of asthma. Little is known of the effects of long-term antigen avoidance and inhaled …