Aging is considered the deterioration of physiological functions along with an increased
mortality rate. This scientific review focuses on the central importance of genomic instability …

Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Saccharomyces cerevisiae is an efficient host for natural-compound production and
preferentially employed in academic studies and bioindustries. However, S. cerevisiae …

Dietary restriction (DR) is the most robust environmental manipulation known to increase
active and healthy lifespan in many species. Despite differences in the protocols and the …

Short-term starvation (or fasting) protects normal cells, mice, and potentially humans from
the harmful side effects of a variety of chemotherapy drugs. Here, we show that treatment …

Saccharomyces cerevisiae has directly or indirectly contributed to the identification of
arguably more mammalian genes that affect aging than any other model organism. Aging in …

Abstract The Human Ageing Genomic Resources (HAGR, http://genomics. senescence. info)
is a freely available online collection of research databases and tools for the biology and …

Aging is the outcome of a balance between damage and repair. The rate of aging and the
appearance of age-related pathology are modulated by stress response and repair …

Methylation of RNA occurs at a variety of atoms, nucleotides, sequences and tertiary
structures. Strongly related to other posttranscriptional modifications, methylation of different …

Background The plasma concentrations of acyl coenzyme A binding protein (ACBP, also
known as diazepam-binding inhibitor, DBI, or 'endozepine') increase with age and obesity …