The antero-posterior heterogeneity of the ventral tegmental area

MJ Sanchez-Catalan, J Kaufling, F Georges… - Neuroscience, 2014 - Elsevier
The ventral tegmental area (VTA) is a brain region processing salient sensory and emotional
information, controlling motivated behaviors, natural or drug-related reward, reward-related …

Old and new biomarkers of alcohol abuse: narrative review

S Fakhari, N Waszkiewicz - Journal of clinical medicine, 2023 - mdpi.com
The harmful use of alcohol is responsible for 5.1% of the global burden of disease, and the
early detection of alcohol problems may prevent its development and progression …

Biomarkers of alcohol misuse: recent advances and future prospects

I Jastrzębska, A Zwolak, M Szczyrek… - Gastroenterology …, 2016 - termedia.pl
Alcohol abuse and dependence are highly prevalent in many cultures and contribute
considerably to the global burden of health and social issues. The current inability to …

Receptor and metabolic insights on the ability of caffeine to prevent alcohol-induced stimulation of mesolimbic dopamine transmission

V Bassareo, R Maccioni, G Talani, S Zuffa… - Translational …, 2024 - nature.com
The consumption of alcohol and caffeine affects the lives of billions of individuals worldwide.
Although recent evidence indicates that caffeine impairs the reinforcing properties of …

Salsolinol: an unintelligible and double-faced molecule—lessons learned from in vivo and in vitro experiments

M Kurnik-Łucka, P Panula, A Bugajski, K Gil - Neurotoxicity Research, 2018 - Springer
Abstract Salsolinol (1-methyl-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline) is a
tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine …

Alcohol-induced alterations in dopamine modulation of prefrontal activity

H Trantham-Davidson, LJ Chandler - Alcohol, 2015 - Elsevier
Long-term alcohol use leads to persistent cognitive deficits that may be associated with
maladaptive changes in the neurocircuitry that mediates executive functions. Impairments …

Mystic acetaldehyde: the never-ending story on alcoholism

AT Peana, MJ Sánchez-Catalán, L Hipólito… - Frontiers in Behavioral …, 2017 - frontiersin.org
After decades of uncertainties and drawbacks, the study on the role and significance of
acetaldehyde in the effects of ethanol seemed to have found its main paths. Accordingly, the …

Ethanol-dependent synthesis of salsolinol in the posterior ventral tegmental area as key mechanism of ethanol's action on mesolimbic dopamine

V Bassareo, R Frau, R Maccioni, P Caboni… - Frontiers in …, 2021 - frontiersin.org
Abnormal consumption of ethanol, the ingredient responsible for alcoholic drinks' addictive
liability, causes millions of deaths yearly. Ethanol's addictive potential is triggered through …

[HTML][HTML] Discovery and validation of banana intake biomarkers using untargeted metabolomics in human intervention and cross-sectional studies

N Vázquez-Manjarrez, CH Weinert… - The Journal of …, 2019 - Elsevier
Background Banana is one of the most widely consumed fruits in the world. However,
information regarding its health effects is scarce. Biomarkers of banana intake would allow a …

Key role of salsolinol in ethanol actions on dopamine neuronal activity of the posterior ventral tegmental area

M Melis, E Carboni, P Caboni, E Acquas - Addiction biology, 2015 - Wiley Online Library
Ethanol excites dopamine (DA) neurons in the posterior ventral tegmental area (pVTA). This
effect is responsible for ethanol's motivational properties and may contribute to alcoholism …