Protein–protein interaction and quaternary structure
Protein–protein recognition plays an essential role in structure and function. Specific non-
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
covalent interactions stabilize the structure of macromolecular assemblies, exemplified in …
Targeted protein degradation: advances, challenges, and prospects for computational methods
The therapeutic approach of targeted protein degradation (TPD) is gaining momentum due
to its potentially superior effects compared with protein inhibition. Recent advancements in …
to its potentially superior effects compared with protein inhibition. Recent advancements in …
The RosettaDock server for local protein–protein docking
S Lyskov, JJ Gray - Nucleic acids research, 2008 - academic.oup.com
Abstract The RosettaDock server (http://rosettadock. graylab. jhu. edu) identifies low-energy
conformations of a protein–protein interaction near a given starting configuration by …
conformations of a protein–protein interaction near a given starting configuration by …
HADDOCK versus HADDOCK: new features and performance of HADDOCK2. 0 on the CAPRI targets
Here we present version 2.0 of HADDOCK, which incorporates considerable improvements
and new features. HADDOCK is now able to model not only protein–protein complexes but …
and new features. HADDOCK is now able to model not only protein–protein complexes but …
Characterization of molecular recognition features, MoRFs, and their binding partners
Mo lecular R ecognition F eatures (MoRFs) are short, interaction-prone segments of protein
disorder that undergo disorder-to-order transitions upon specific binding, representing a …
disorder that undergo disorder-to-order transitions upon specific binding, representing a …
Computer-aided antibody design
Recent clinical trials using antibodies with low toxicity and high efficiency have raised
expectations for the development of next-generation protein therapeutics. However, the …
expectations for the development of next-generation protein therapeutics. However, the …
Predicting protein-protein interactions on a proteome scale by matching evolutionary and structural similarities at interfaces using PRISM
Prediction of protein-protein interactions at the structural level on the proteome scale is
important because it allows prediction of protein function, helps drug discovery and takes …
important because it allows prediction of protein function, helps drug discovery and takes …
pyDock: Electrostatics and desolvation for effective scoring of rigid‐body protein–protein docking
The accurate scoring of rigid‐body docking orientations represents one of the major
difficulties in protein–protein docking prediction. Other challenges are the development of …
difficulties in protein–protein docking prediction. Other challenges are the development of …
Recent progress and future directions in protein-protein docking
DW Ritchie - Current protein and peptide science, 2008 - ingentaconnect.com
This article gives an overview of recent progress in protein-protein docking and it identifies
several directions for future research. Recent results from the CAPRI blind docking …
several directions for future research. Recent results from the CAPRI blind docking …
An iterative knowledge‐based scoring function for protein–protein recognition
SY Huang, X Zou - Proteins: Structure, Function, and …, 2008 - Wiley Online Library
Using an efficient iterative method, we have developed a distance‐dependent knowledge‐
based scoring function to predict protein–protein interactions. The function, referred to as …
based scoring function to predict protein–protein interactions. The function, referred to as …