Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

High-density lipoprotein (HDL) has been proposed to have several antiatherosclerotic
properties, including the ability to mediate macrophage cholesterol efflux, antioxidant …

Lipopolysaccharide (LPS), the major component of the outer membrane of Gram-negative
bacteria, binds Toll-like receptor 4 (TLR4)-MD2 complex and activates innate immune …

Lipid abnormalities are among the key risk factors for cardiovascular disease. Indeed, lipid-
modifying drugs—in particular, the statins, which primarily lower plasma levels of low …

Cholesteryl ester transfer protein (CETP) shuttles various lipids between lipoproteins,
resulting in the net transfer of cholesteryl esters from atheroprotective, high-density …

The upper respiratory tract, including the nasal and oral cavities, is the major route of entry of
pathogens into the body, and early recognition of bacterial products in this region is critical …

High-density lipoproteins (HDL) play a major protective role against the development of
coronary artery disease. Phospholipid transfer protein (PLTP) is a main factor regulating the …

Abstract Purpose of Review Cholesteryl ester transfer proteins (CETP) regulate plasma
cholesterol levels by transferring cholesteryl esters (CEs) among lipoproteins. Lipoprotein …

Increased secretion and levels of ApoB-containing lipoproteins (BLp) commonly occur in
familial hyperlipidemia, obesity and diabetes. The plasma phospholipid-transfer protein …

Most of the cholesterol in plasma is in an esterified form that is generated in potentially
cardioprotective HDLs. Cholesteryl ester transfer protein (CETP) mediates bidirectional …