Extracellular vesicle nanoarchitectonics for novel drug delivery applications

S Sharma, MK Masud, YV Kaneti, P Rewatkar… - Small, 2021 - Wiley Online Library
Extracellular vesicles (EVs) can transfer intercellular messages in various (patho)
physiological processes and transport biomolecules to recipient cells. EVs possess the …

Insights into drug loading techniques with mesoporous silica nanoparticles: Optimization of operating conditions and assessment of drug stability

AH Khalbas, TM Albayati, NMC Saady… - Journal of Drug Delivery …, 2024 - Elsevier
Mesoporous silica nanoparticles (MSNs) are promising inorganic materials for oral drug
delivery due to their unique characteristics, such as tunable pore size, high surface area …

Strategic developments in polymer-functionalized liposomes for targeted colon cancer therapy: an updated review of clinical trial data and future horizons

S Sharma, M Chakraborty, D Yadav, A Dhullap… - …, 2024 - ACS Publications
Liposomes, made up of phospholipid bilayers, are efficient nanocarriers for drug delivery
because they can encapsulate both hydrophilic and lipophilic drugs. Conventional cancer …

[HTML][HTML] Tailoring functional nanoparticles for oral vaccine delivery: Recent advances and future perspectives

P Cao, ZP Xu, L Li - Composites Part B: Engineering, 2022 - Elsevier
The oral vaccine has attracted much interest due to easy administration, induction of local
and systemic immune responses, and pain relief. Nowadays, functional nanoparticles and …

[HTML][HTML] Phlorotannins: novel orally administrated bioactive compounds that induce mitochondrial dysfunction and oxidative stress in cancer

L Simón, M Arazo-Rusindo, AFG Quest… - Antioxidants, 2023 - mdpi.com
Mitochondrial dysfunction is an interesting therapeutic target to help reduce cancer deaths,
and the use of bioactive compounds has emerged as a novel and safe approach to solve …

Delivery of natural agents by means of mesoporous silica nanospheres as a promising anticancer strategy

K AbouAitah, W Lojkowski - Pharmaceutics, 2021 - mdpi.com
Natural prodrugs derived from different natural origins (eg, medicinal plants, microbes,
animals) have a long history in traditional medicine. They exhibit a broad range of …

[HTML][HTML] Physical characterization of clove oil based self Nano-emulsifying formulations of cefpodoxime proxetil: Assessment of dissolution rate, antioxidant & …

A **dal, A Kumar - OpenNano, 2022 - Elsevier
Cefpodoxime proxetil (CPD) is a broad-spectrum cephalosporin widely indicated in
respiratory tract infections like pneumonia. CPD is a BCS class IV drug with the constraint of …

Mesoporous silica nanoparticles improve oral delivery of antitubercular bicyclic nitroimidazoles

CW Ang, L Tan, Z Qu, NP West… - ACS biomaterials …, 2021 - ACS Publications
Pretomanid and MCC7433, a novel nitroimidazopyrazinone analog, are promising
antitubercular agents that belong to the bicyclic nitroimidazole family. Despite possessing …

Engineered Urolithin A-laden functional polymer-lipid hybrid nanoparticles prevent cisplatin-induced proximal tubular injury in vitro

W Pula, R Ganugula, E Esposito, MNVR Kumar… - European Journal of …, 2024 - Elsevier
Functional polymer-lipid hybrid nanoparticles (H-NPs) are a promising class of nanocarriers
that combine the benefits of polymer and lipid nanoparticles, offering biocompatibility …

Bio-intelligent plasma-engineered diferuloylmethane/fucoidan/neutrophil lysate/iron oxide nanoclusters for phototherapeutic and magnetotherapeutic with in situ …

AEY Chuang, YW Lin, PR Jheng, L Rethi… - Colloids and Surfaces B …, 2024 - Elsevier
Creating a versatile and remotely self-assembling biocomposite for delivering therapeutics
to alleviate inflammatory diseases poses significant challenges. This study introduces a …