COVID‐19 and toll‐like receptor 4 (TLR4): SARS‐CoV‐2 may bind and activate TLR4 to increase ACE2 expression, facilitating entry and causing hyperinflammation
MM Aboudounya, RJ Heads - Mediators of inflammation, 2021 - Wiley Online Library
Causes of mortality from COVID‐19 include respiratory failure, heart failure, and
sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that …
sepsis/multiorgan failure. TLR4 is an innate immune receptor on the cell surface that …
Environmental stressors on skin aging. Mechanistic insights
C Parrado, S Mercado-Saenz, A Perez-Davo… - Frontiers in …, 2019 - frontiersin.org
The skin is the main barrier that protects us against environmental stressors (physical,
chemical, and biological). These stressors, combined with internal factors, are responsible …
chemical, and biological). These stressors, combined with internal factors, are responsible …
In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs
A Choudhury, S Mukherjee - Journal of medical virology, 2020 - Wiley Online Library
Abstract Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as …
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as …
Zoonotic spillover: Understanding basic aspects for better prevention
The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …
Most human infectious diseases (60-75%) are derived from pathogens that originally …
Toll‐like receptor polymorphism in host immune response to infectious diseases: A review
S Mukherjee, S Huda… - Scandinavian journal of …, 2019 - Wiley Online Library
Immunopolymorphism is considered as an important aspect behind the resistance or
susceptibility of the host to an infectious disease. Over the years, researchers have explored …
susceptibility of the host to an infectious disease. Over the years, researchers have explored …
[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?
A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …
Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives
Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …
pathogen-expressed molecules and host-derived molecules released from damaged or …
Bacillus siamensis Targeted Screening from Highly Colitis-Resistant Pigs Can Alleviate Ulcerative Colitis in Mice
X Fang, H Liu, Y Du, L Jiang, F Gao, Z Wang, Z Chi… - Research, 2024 - spj.science.org
Ulcerative colitis (UC) is often accompanied by intestinal inflammation and disruption of
intestinal epithelial structures, which are closely associated with changes in the intestinal …
intestinal epithelial structures, which are closely associated with changes in the intestinal …
Sulforaphane: its “coming of age” as a clinically relevant nutraceutical in the prevention and treatment of chronic disease
CA Houghton - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
A growing awareness of the mechanisms by which phytochemicals can influence upstream
endogenous cellular defence processes has led to intensified research into their potential …
endogenous cellular defence processes has led to intensified research into their potential …
Antiviral and immunomodulatory effects of phytochemicals from honey against COVID-19: Potential mechanisms of action and future directions
The new coronavirus disease (COVID-19), caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), has recently put the world under stress, resulting in a global …
coronavirus-2 (SARS-CoV-2), has recently put the world under stress, resulting in a global …