Emerging roles for serotonin in regulating metabolism: new implications for an ancient molecule

JM Yabut, JD Crane, AE Green, DJ Keating… - Endocrine …, 2019 - academic.oup.com
Serotonin is a phylogenetically ancient biogenic amine that has played an integral role in
maintaining energy homeostasis for billions of years. In mammals, serotonin produced …

Gut microbiota metabolites in NAFLD pathogenesis and therapeutic implications

J Chen, L Vitetta - International journal of molecular sciences, 2020 - mdpi.com
Gut microbiota dysregulation plays a key role in the pathogenesis of nonalcoholic fatty liver
disease (NAFLD) through its metabolites. Therefore, the restoration of the gut microbiota and …

The ever-changing roles of serotonin

LA Jones, EW Sun, AM Martin, DJ Keating - The international journal of …, 2020 - Elsevier
Abstract Serotonin (5-HT) has traditional roles as a key neurotransmitter in the central
nervous system and as a regulatory hormone controlling a broad range of physiological …

Intestinal dysbiosis in nonalcoholic fatty liver disease (NAFLD): focusing on the gut–liver axis

H Han, Y Jiang, M Wang, M Melaku, L Liu… - Critical reviews in …, 2023 - Taylor & Francis
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders
in humans, partly because it is closely related to metabolic disorders of the liver with …

State-of-the-art review of theabrownins: from preparation, structural characterization to health-promoting benefits

L Cheng, Y Wei, L Peng, K Wei, Z Liu… - Critical Reviews in Food …, 2024 - Taylor & Francis
As far as health benefit is concerned, dark tea is one of the best beverages in the world.
Theabrownins are the major ingredient contributing to the health benefits of dark tea and …

The role of the gut microbiota in lipid and lipoprotein metabolism

Y Yu, F Raka, K Adeli - Journal of clinical medicine, 2019 - mdpi.com
Both environmental and genetic factors contribute to relative species abundance and
metabolic characteristics of the intestinal microbiota. The intestinal microbiota and …

[HTML][HTML] Theabrownin inhibits obesity and non-alcoholic fatty liver disease in mice via serotonin-related signaling pathways and gut-liver axis

HY Li, SY Huang, DD Zhou, RG **ong, M Luo… - Journal of Advanced …, 2023 - Elsevier
Introduction Non-alcoholic fatty liver disease (NAFLD) with obesity seriously threats public
health. Our previous studies showed that dark tea had more potential on regulating lipid …

The relationship between the serotonin metabolism, gut-microbiota and the gut-brain axis

C Stasi, S Sadalla, S Milani - Current drug metabolism, 2019 - ingentaconnect.com
Background: Serotonin (5-HT) has a pleiotropic function in gastrointestinal, neurological/
psychiatric and liver diseases. The aim of this review was to elucidate whether the gut …

Inhibiting serotonin signaling through HTR2B in visceral adipose tissue improves obesity-related insulin resistance

WG Choi, W Choi, TJ Oh, HN Cha… - The Journal of …, 2021 - Am Soc Clin Investig
Insulin resistance is a cornerstone of obesity-related complications such as type 2 diabetes,
metabolic syndrome, and nonalcoholic fatty liver disease. A high rate of lipolysis is known to …

Postprandial metabolomics analysis reveals disordered serotonin metabolism in post-bariatric hypoglycemia

R Ferraz-Bannitz, B Ozturk, C Cummings… - The Journal of Clinical …, 2024 - jci.org
BACKGROUND Bariatric surgery is a potent therapeutic approach for obesity and type 2
diabetes but can be complicated by post-bariatric hypoglycemia (PBH). PBH typically occurs …