Mesenchymal stem/stromal cells (MSCs) are multipotent cells that are emerging as the most
promising means of allogeneic cell therapy. MSCs have inherent immunomodulatory …

OA is now well accepted as a low-grade inflammatory disease affecting the whole joint. In
addition to mechanical loading, inflammation (particularly synovitis), contributes significantly …

Cartilage lesions and osteoarthritis (OA) presents an ever-increasing clinical and
socioeconomic burden. Synovial inflammation and articular inflammatory environment are …

Objectives To investigate the roles and regulatory mechanisms of synovial macrophages
and their polarisation in the development of osteoarthritis (OA). Methods Synovial tissues …

Introduction Platelet-rich plasma (PRP) is able to modulate the joint environment by
reducing the inflammatory distress and promoting tissue anabolism. Therefore, it has gained …

The prevalence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, yet there
are no effective treatments. A decade has passed since the initial lipidomics analyses of liver …

Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments.
Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical …

Mesenchymal stem cells (MSCs) are regarded as highly promising cells for allogeneic cell
therapy, owing to their multipotent nature and ability to display potent and varied functions in …

Osteoarthritis (OA) is a common joint condition that is a leading cause of disability
worldwide. There are currently no disease-modifying treatments for osteoarthritis, which is …

Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …