The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

The use of heart rate variability (HRV) in research has been greatly popularized over the
past decades due to the ease and affordability of HRV collection, coupled with its clinical …

Photoplethysmography is a key sensing technology which is used in wearable devices such
as smartwatches and fitness trackers. Currently, photoplethysmography sensors are used to …

Evidence suggests affective disorders such as depression and bipolar disorder are
characterised by dysregulated autonomic nervous system (ANS) activity. These findings …

Objectives Burnout is a state of exhaustion resulting from prolonged and excessive
workplace stress. We sought to examine biological underpinnings of burnout, focussing on …

BackgroundMajor depression (MD) is a risk factor for cardiovascular disease. Reduced
heart rate variability (HRV) has been observed in MD. Given the predictive value of HRV for …

Psychophysiological research integrating heart rate variability (HRV) has increased during
the last two decades, particularly given the fact that HRV is able to index cardiac vagal tone …

Background Heart rate variability is used as an assessment method for cardiac autonomic
modulation. Since the Task Force's publication on heart rate variability in 1996, the …

Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

Background: Depression diagnosis requires five or more symptoms (Diagnostic and
Statistical Manual of Mental Disorders-DSM-5). One of them must be either Depressed mood …