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Microbial tryptophan catabolites in health and disease
Accumulating evidence implicates metabolites produced by gut microbes as crucial
mediators of diet-induced host-microbial cross-talk. Here, we review emerging data …
mediators of diet-induced host-microbial cross-talk. Here, we review emerging data …
[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - researchgate.net
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
Sesterterpenoids
L Wang, B Yang, XP Lin, XF Zhou, Y Liu - Natural product reports, 2013 - pubs.rsc.org
Covering: October 2006 to June 2012 This review, with 166 references, covers the literature
published on sesterterpenoids together with their relevant biological activities, source …
published on sesterterpenoids together with their relevant biological activities, source …
Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning
M Kaiser, P Mäser, LP Tadoori, JR Ioset, R Brun - PloS one, 2015 - journals.plos.org
Neglected tropical diseases cause significant morbidity and mortality and are a source of
poverty in endemic countries. Only a few drugs are available to treat diseases such as …
poverty in endemic countries. Only a few drugs are available to treat diseases such as …
Antitrypanosomal Quinoline Alkaloids from the Roots of Waltheria indica
S Cretton, L Breant, L Pourrez, C Ambuehl… - Journal of natural …, 2014 - ACS Publications
Chemical investigation of the dichloromethane root extract of Waltheria indica led to the
isolation and characterization of 10 quinoline alkaloids, namely, 8-deoxoantidesmone (1) …
isolation and characterization of 10 quinoline alkaloids, namely, 8-deoxoantidesmone (1) …
Progress in the chemistry of organic natural products
Termites (Isoptera), which are a suborder of the cockroaches, are the oldest eusocial insects
[1–3]. It is assumed that they diverged from the Cryptocercoidae, woodfeeding cockroaches …
[1–3]. It is assumed that they diverged from the Cryptocercoidae, woodfeeding cockroaches …
Novel 3-Nitro-1H-1,2,4-triazole-Based Amides and Sulfonamides as Potential Antitrypanosomal Agents
MV Papadopoulou, WD Bloomer… - Journal of Medicinal …, 2012 - ACS Publications
A series of novel 3-nitro-1 H-1, 2, 4-triazole-based (and in some cases 2-nitro-1 H-imidazole-
based) amides and sulfonamides were characterized for their in vitro antitrypanosomal and …
based) amides and sulfonamides were characterized for their in vitro antitrypanosomal and …
The Laurencia Paradox: An Endless Source of Chemodiversity
Nature, the most prolific source of biological and chemical diversity, has provided mankind
with treatments for health problems since ancient times and continues to be the most …
with treatments for health problems since ancient times and continues to be the most …
Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds
Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants,
bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and …
bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and …
Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus ileboensis with potent activities against …
J Li, R Seupel, D Feineis, V Mudogo… - Journal of natural …, 2017 - ACS Publications
Dioncophylline F (1), the first 5, 8′-coupled dioncophyllaceous alkaloid (ie, lacking an
oxygen function at C-6 and possessing an R-configuration at C-3), was isolated from the …
oxygen function at C-6 and possessing an R-configuration at C-3), was isolated from the …