[HTML][HTML] Tackling Drug-Resistant Tuberculosis: New Challenges from the Old Pathogen Mycobacterium tuberculosis

G Mancuso, A Midiri, S De Gaetano, E Ponzo… - Microorganisms, 2023 - mdpi.com
Antibiotics have played a crucial role in the reduction in the incidence of TB globally as
evidenced by the fact that before the mid-20th century, the mortality rate within five years of …

Genomic Interactions Between Mycobacterium tuberculosis and Humans

P Palittapongarnpim, P Tantivitayakul… - Annual Review of …, 2024 - annualreviews.org
Mycobacterium tuberculosis is considered by many to be the deadliest microbe, with the
estimated annual cases numbering more than 10 million. The bacteria, including …

Population structure and spatial distribution of Mycobacterium tuberculosis in Ethiopia

M Getahun, D Beyene, H Mollalign, G Diriba… - Scientific reports, 2024 - nature.com
Ethiopia is one of the countries with a high tuberculosis (TB) burden, yet little is known about
the spatial distribution of Mycobacterium tuberculosis (Mtb) lineages. This study identifies …

Mycobacterium tuberculosis Sub-Lineage 4.2.2/SIT149 as Dominant Drug-Resistant Clade in Northwest Ethiopia 2020–2022: In-silico Whole-Genome Sequence …

D Mekonnen, A Munshea, E Nibret… - Infection and Drug …, 2023 - Taylor & Francis
Introduction Drug resistance (DR) in Mycobacterium tuberculosis complex (MTBC) is mainly
associated with certain lineages and varies across regions and countries. The Bei**g …

A revised SNP-based barcoding scheme for ty** Mycobacterium tuberculosis complex isolates

E Shitikov, D Bespiatykh - MSphere, 2023 - journals.asm.org
The development of whole-genome sequencing technologies is gradually leading to a more
detailed description of the population structure of the Mycobacterium tuberculosis complex …

fastlin: an ultra-fast program for Mycobacterium tuberculosis complex lineage ty**

R Derelle, J Lees, J Phelan, A Lalvani… - …, 2023 - academic.oup.com
Fastlin is a bioinformatics tool designed for rapid Mycobacterium tuberculosis complex
(MTBC) lineage ty**. It utilizes an ultra-fast alignment-free approach to detect previously …

Comparative whole-genome sequence analysis of Mycobacterium tuberculosis isolated from pulmonary tuberculosis and tuberculous lymphadenitis patients in …

D Mekonnen, A Munshea, E Nibret, B Adnew… - Frontiers in …, 2023 - frontiersin.org
Background Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex (MTBC),
is a chronic infectious disease with both pulmonary and extrapulmonary forms. This study …

TBtypeR: Sensitive detection and sublineage classification of Mycobacterium tuberculosis complex mixed-strain infections

JE Munro, AK Coussens, M Bahlo - Communications Biology, 2025 - nature.com
Tuberculosis (TB) is typically attributed to a single infecting strain of the Mycobacterium
tuberculosis Complex (MTBC), however mixed-strain infections are more common than …

Distribution of Mycobacterium tuberculosis Lineages and Drug Resistance in Upper Myanmar

AN Phyu, ST Aung, P Palittapongarnpim… - Tropical Medicine and …, 2022 - mdpi.com
Mycobacterium tuberculosis complex (MTBC) is divided into 9 whole genome sequencing
(WGS) lineages. Among them, lineages 1–4 are widely distributed. Multi-drug resistant …

Genomic Sequencing Profiles of Mycobacterium tuberculosis in Mandalay Region, Myanmar

AN Phyu, ST Aung, P Palittapongarnpim… - Tropical Medicine and …, 2023 - mdpi.com
This study aimed to characterize whole-genome sequencing (WGS) information of
Mycobacterium tuberculosis (Mtb) in the Mandalay region of Myanmar. It was a cross …