Recent Advances in the Study of Na+/K+-ATPase in Neurodegenerative Diseases
Na+/K+-ATPase (NKA), a large transmembrane protein, is expressed in the plasma
membrane of most eukaryotic cells. It maintains resting membrane potential, cell volume and …
membrane of most eukaryotic cells. It maintains resting membrane potential, cell volume and …
Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein
ADG Leitão, P Rudolffi-Soto, A Chappard… - Communications …, 2021 - nature.com
The aggregation of alpha-synuclein (α-SYN) follows a cascade of oligomeric, prefibrillar and
fibrillar forms, culminating in the formation of Lewy Bodies (LB), the pathological hallmarks of …
fibrillar forms, culminating in the formation of Lewy Bodies (LB), the pathological hallmarks of …
Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress
Z Cui, FY Guo, L Li, F Lu, CH **, X Wang… - European Journal of …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by the
accumulation of α-synuclein (α-Syn) aggregates. However, there are currently no effective …
accumulation of α-synuclein (α-Syn) aggregates. However, there are currently no effective …
Using a stable protein scaffold to display peptides that bind to alpha-synuclein fibrils
S Bismut, MM Schneider, M Miyasaki, Y Feng, EJ Wilde… - bioRxiv, 2025 - biorxiv.org
Amyloid fibrils are ordered aggregates that are a pathological hallmark of many
neurodegenerative disorders including Alzheimer′ s Disease and Parkinson′ s Disease …
neurodegenerative disorders including Alzheimer′ s Disease and Parkinson′ s Disease …