Interleukin-1 family cytokines: keystones in liver inflammatory diseases

L Barbier, M Ferhat, E Salamé, A Robin… - Frontiers in …, 2019 - frontiersin.org
The pyrogenic property being the first activity described, members of the interleukin-1
superfamily (IL-1α, IL-1β, IL-18, and the newest members: IL-33, IL-36, IL-37, and IL-38) are …

Evolution and diversity of immune responses during acute HIV infection

SW Kazer, BD Walker, AK Shalek - Immunity, 2020 - cell.com
Understanding the earliest immune responses following HIV infection is critical to inform
future vaccines and therapeutics. Here, we review recent prospective human studies in at …

Human CD56dimCD16dim Cells As an Individualized Natural Killer Cell Subset

M Amand, G Iserentant, A Poli, M Sleiman… - Frontiers in …, 2017 - frontiersin.org
Human natural killer (NK) cells can be subdivided in several subpopulations on the basis of
the relative expression of the adhesion molecule CD56 and the activating receptor CD16 …

Transcription factor IRF8 orchestrates the adaptive natural killer cell response

NM Adams, CM Lau, X Fan, M Rapp, CD Geary… - Immunity, 2018 - cell.com
Natural killer (NK) cells are innate lymphocytes that display features of adaptive immunity
during viral infection. Biallelic mutations in IRF8 have been reported to cause familial NK cell …

HLA Class Ib-receptor interactions during embryo implantation and early pregnancy

LL Nilsson, TVF Hviid - Human reproduction update, 2022 - academic.oup.com
BACKGROUND Although the immune system intuitively must have an important role in
embryo implantation and in the achievement of a pregnancy, the molecular details have for …

Chimeric antigen receptor (CAR)-modified natural killer cell-based immunotherapy and immunological synapse formation in cancer and HIV

D Liu, S Tian, K Zhang, W **ong, NM Lubaki… - Protein & …, 2017 - academic.oup.com
Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells contribute to the body's immune
defenses. Current chimeric antigen receptor (CAR)-modified T cell immunotherapy shows …

[HTML][HTML] CAR-based strategies beyond T lymphocytes: integrative opportunities for cancer adoptive immunotherapy

R Rotolo, V Leuci, C Donini, A Cykowska… - International Journal of …, 2019 - mdpi.com
Chimeric antigen receptor (CAR)-engineered T lymphocytes (CAR Ts) produced impressive
clinical results against selected hematological malignancies, but the extension of CAR T cell …

[HTML][HTML] The folate cycle as a cause of natural killer cell dysfunction and viral etiology in type 1 diabetes

AL Bayer, CA Fraker - Frontiers in Endocrinology, 2017 - frontiersin.org
The folate pathway is critical to proper cellular function and metabolism. It is responsible for
multiple functions, including energy (ATP) production, methylation reactions for DNA and …

[HTML][HTML] Increased Complement Receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms

R Gupta, VA Gant, B Williams, T Enver - International journal of infectious …, 2020 - Elsevier
Background The reasons why some patients with COVID-19 develop pneumonia and others
do not are unclear. To better understand this, we used multiparameter flow cytometry to …

Immunogenicity of botulinum toxin A: insights

E Rahman, JDA Carruthers - Dermatologic Surgery, 2024 - journals.lww.com
BACKGROUND Botulinum toxin A (BoNT-A) is widely used in treating dystonia and
spasticity to managing chronic migraine and cosmetic applications. However, its …