The promise of automated machine learning for the genetic analysis of complex traits
The genetic analysis of complex traits has been dominated by parametric statistical methods
due to their theoretical properties, ease of use, computational efficiency, and intuitive …
due to their theoretical properties, ease of use, computational efficiency, and intuitive …
Excitability mediates allocation of pre-configured ensembles to a hippocampal engram supporting contextual conditioned threat in mice
Little is understood about how engrams, sparse groups of neurons that store memories, are
formed endogenously. Here, we combined calcium imaging, activity tagging, and …
formed endogenously. Here, we combined calcium imaging, activity tagging, and …
A one-photon endoscope for simultaneous patterned optogenetic stimulation and calcium imaging in freely behaving mice
Optogenetics and calcium imaging can be combined to simultaneously stimulate and record
neural activity in vivo. However, this usually requires two-photon microscopes, which are not …
neural activity in vivo. However, this usually requires two-photon microscopes, which are not …
Electrical signaling and coordinated behavior in the closest relative of animals
J Colgren, P Burkhardt - Science Advances, 2025 - science.org
The transition from simple to complex multicellularity involves division of labor and
specialization of cell types. In animals, complex sensory-motor systems are primarily built …
specialization of cell types. In animals, complex sensory-motor systems are primarily built …
Automatic machine learning combined with high-throughput computational screening of hydrophobic metal–organic frameworks for capture of methanol and ethanol …
L Zhang, Q Huang, L Li, Y Yan, XY Yuan… - ACS ES&T …, 2023 - ACS Publications
The capture of low concentration alcohol VOCs (methanol and ethanol) from the air has also
attracted more and more attention. In this work, high-throughput computational screening …
attracted more and more attention. In this work, high-throughput computational screening …
Activity patterns of individual neurons and ensembles correlated with retrieval of a contextual memory in the dorsal CA1 of mouse hippocampus
HS Lee, JH Han - Journal of Neuroscience, 2023 - Soc Neuroscience
The hippocampus is crucial for retrieval of contextual memories. The activation of a
subpopulation of neurons in the dorsal CA1 (dCA1) of the hippocampus is required for …
subpopulation of neurons in the dorsal CA1 (dCA1) of the hippocampus is required for …
Review of data processing of functional optical microscopy for neuroscience
Functional optical imaging in neuroscience is rapidly growing with the development of
optical systems and fluorescence indicators. To realize the potential of these massive …
optical systems and fluorescence indicators. To realize the potential of these massive …
Diving into AutoML in Medical Imaging: Solution for Non-ML Practitioners
Within the healthcare sector, deploying Machine Learning (ML) models involves trial-and-
error approaches, considerable time to create task-specific models, and collaboration …
error approaches, considerable time to create task-specific models, and collaboration …
Custom-built operant conditioning setup for calcium imaging and cognitive testing in freely moving mice
P Vassilev, E Fonseca, G Hernandez… - Eneuro, 2022 - eneuro.org
Operant chambers are widely used in animal research to study cognition, motivation, and
learning processes. Paired with the rapidly develo** technologies for brain imaging and …
learning processes. Paired with the rapidly develo** technologies for brain imaging and …
Open-source software for real-time calcium imaging and synchronized neuron firing detection
We developed Carignan, a real-time calcium imaging software that can automatically detect
activity patterns of neurons. Carignan can activate an external device when synchronized …
activity patterns of neurons. Carignan can activate an external device when synchronized …