Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability
Alzheimer's disease (AD) is a devastating neurodegenerative condition that affects memory
and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in …
and cognition, characterized by neuronal loss and currently lacking a cure. Mutations in …
MALDI-2-enabled oversampling for the mass spectrometry imaging of metabolites at single-cell resolution
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
provide valuable insights into the metabolome of complex biological systems such as organ …
provide valuable insights into the metabolome of complex biological systems such as organ …
Visualization of incrementally learned projection trajectories for longitudinal data
Longitudinal studies that continuously generate data enable the capture of temporal
variations in experimentally observed parameters, facilitating the interpretation of results in a …
variations in experimentally observed parameters, facilitating the interpretation of results in a …
Astrocytic glutamate regulation is implicated in the development of stress-related psychiatric disorders
Severe psychological stress is one of the most potent risk factors for develo** a mood or
psychotic disorder, yet the underlying molecular mechanisms are poorly understood …
psychotic disorder, yet the underlying molecular mechanisms are poorly understood …
Dynamic balance of H3K9me2 heterochromatin by CoREST-2 and RE-1 in growing neurons
JF Drube, A Cardozo-Gizzi, V Rozes-Salvador… - bioRxiv, 2025 - biorxiv.org
A well-balanced chromatin dynamic is vital for the survival and physiology of all cells,
including brain neurons. Heterochromatin, commonly associated with transcriptional …
including brain neurons. Heterochromatin, commonly associated with transcriptional …
THE EFFECT OF SERTRALINE AND VOLUNTARY EXERCISE DURING PREGNANCY ON LITTER CHARACTERISTICS AND POSTNATAL AFFECTIVE BEHAVIOUR …
NS Jarbou, O Mairinger, E Kulen, L Mushahwar… - bioRxiv, 2025 - biorxiv.org
Introduction: Sertraline is the frontline pharmacotherapy for the treatment of depression and
anxiety during pregnancy. However, there is little evidence regarding the effects of sertraline …
anxiety during pregnancy. However, there is little evidence regarding the effects of sertraline …