Since the first pioneering studies on small deuterated peptides dating more than 20 years
ago, 1H detection has evolved into the most efficient approach for investigation of …

NMR spectroscopy is a powerful tool for biologists interested in the structure, dynamics, and
interactions of biological macromolecules. This review aims at presenting in an accessible …

Abstract Background ACPYPE (or AnteChamber PYthon Parser interfacE) is a wrapper
script around the ANTECHAMBER software that simplifies the generation of small molecule …

Expression of the INK4b/ARF/INK4a tumor suppressor locus in normal and cancerous cell
growth is controlled by methylation of histone H3 at lysine 27 (H3K27me) as directed by the …

The BioMagResBank (BMRB: www. bmrb. wisc. edu) is a repository for experimental and
derived data gathered from nuclear magnetic resonance (NMR) spectroscopic studies of …

The automated assignment of NOESY cross peaks has become a fundamental technique for
NMR protein structure analysis. A widely used algorithm for this purpose is implemented in …

Formation of amyloid-beta (Aβ) oligomer pores in the membrane of neurons has been
proposed to explain neurotoxicity in Alzheimerʼs disease (AD). Here, we present the three …

In cancer, the programmed death-1 (PD-1) pathway suppresses T cell stimulation and
mediates immune escape. Upon stimulation, PD-1 becomes phosphorylated at its immune …

The 2019 novel respiratory virus (SARS-CoV-2) causes COVID-19 with rapid global
socioeconomic disruptions and disease burden to healthcare. The COVID-19 and previous …

BRD4-NUT, a driver fusion mutant in rare and highly aggressive NUT carcinoma, acts in
aberrant transcription of anti-differentiation genes by recruiting histone acetyltransferase …