Recent updates on drug resistance in Mycobacterium tuberculosis

R Singh, SP Dwivedi, US Gaharwar… - Journal of applied …, 2020 - academic.oup.com
Tuberculosis (TB) along with acquired immune deficiency syndrome and malaria rank
among the top three fatal infectious diseases which pose threat to global public health …

Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

JA Caminero, G Sotgiu, A Zumla… - The Lancet infectious …, 2010 - thelancet.com
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally
thought to have high mortality rates. However, many cases can be treated with the right …

[BOOK][B] WHO consolidated guidelines on tuberculosis. Module 4: treatment-drug-resistant tuberculosis treatment, 2022 update

World Health Organization - 2022 - books.google.com
The WHO Consolidated Guidelines on Tuberculosis (TB), Module 4: Treatment-Drug-
Resistant Tuberculosis Treatment 2022 update informs health care professionals in Member …

[BOOK][B] WHO consolidated guidelines on drug-resistant tuberculosis treatment

World Health Organization - 2019 - apps.who.int
Executive summary Tuberculosis (TB) strains with drug resistance (DR-TB) are more difficult
to treat than drug-susceptible ones, and threaten global progress towards the targets set by …

[BOOK][B] Guidelines for the programmatic management of drug-resistant tuberculosis: emergency update 2008

World Health Organization - 2008 - apps.who.int
The emergence in 2006 of extensively drug-resistant strains of tuberculosis, especially in
countries with a high prevalence of human immunodeficiency virus, are serious threats to …

Multidrug resistant pulmonary tuberculosis treatment regimens and patient outcomes: an individual patient data meta-analysis of 9,153 patients

SD Ahuja, D Ashkin, M Avendano, R Banerjee… - 2012 - journals.plos.org
Background Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic,
expensive, and has generally poor outcomes. We undertook an individual patient data meta …

Mechanisms of Drug Resistance in Mycobacterium tuberculosis

Y Zhang, C Vilchèze… - Tuberculosis and the …, 2004 - Wiley Online Library
Drug resistance in tuberculosis (TB) is a particular problem because the lengthy therapy of
at least 6 months makes patient compliance very difficult, which frequently creates drug …

The path of anti-tuberculosis drugs: from blood to lesions to mycobacterial cells

V Dartois - Nature Reviews Microbiology, 2014 - nature.com
For the successful treatment of pulmonary tuberculosis, drugs need to penetrate complex
lung lesions and permeate the mycobacterial cell wall in order to reach their intracellular …

Treatment outcomes of multidrug-resistant tuberculosis: a systematic review and meta-analysis

JC Johnston, NC Shahidi, M Sadatsafavi… - PloS one, 2009 - journals.plos.org
Background Treatment outcomes for multidrug-resistant Mycobacterium Tuberculosis
(MDRTB) are generally poor compared to drug sensitive disease. We sought to estimate …

[CITATION][C] WHO guidelines for the programmatic management of drug-resistant tuberculosis: 2011 update

D Falzon, E Jaramillo, HJ Schünemann, M Arentz… - 2011 - Eur Respiratory Soc