[HTML][HTML] Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals

G Delbes, M Blázquez, JI Fernandino, P Grigorova… - Environmental …, 2022 - Elsevier
Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs)
have an impact on reproductive health. An increased frequency of reproductive disorders …

[HTML][HTML] Combined toxicity of endocrine-disrupting chemicals: A review

N Hamid, M Junaid, DS Pei - Ecotoxicology and environmental safety, 2021 - Elsevier
The combined toxicological assessment provides a realistic approach for hazard evaluation
of chemical cocktails that co-existed in the environment. This review provides a holistic …

Effect-based tools for monitoring and predicting the ecotoxicological effects of chemicals in the aquatic environment

RE Connon, J Geist, I Werner - Sensors, 2012 - mdpi.com
Ecotoxicology faces the challenge of assessing and predicting the effects of an increasing
number of chemical stressors on aquatic species and ecosystems. Herein we review …

[HTML][HTML] Towards regulation of Endocrine Disrupting chemicals (EDCs) in water resources using bioassays–A guide to develo** a testing strategy

J Robitaille, ND Denslow, BI Escher… - Environmental …, 2022 - Elsevier
Endocrine disrupting chemicals (EDCs) are found in every environmental medium and are
chemically diverse. Their presence in water resources can negatively impact the health of …

Estrogen regulation of gene expression in the teleost fish immune system

MA Burgos-Aceves, A Cohen, Y Smith… - Fish & shellfish …, 2016 - Elsevier
Elucidating the mechanisms of estrogens-induced immunomodulation in teleost fish is of
great importance due to the observed worldwide continuing decrease in pristine …

Mixture toxicity revisited from a toxicogenomic perspective

R Altenburger, S Scholz… - … science & technology, 2012 - ACS Publications
The advent of new genomic techniques has raised expectations that central questions of
mixture toxicology such as for mechanisms of low dose interactions can now be answered …

Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2, 4-dichlorophenol

Y Ma, J Han, Y Guo, PKS Lam, RSS Wu, JP Giesy… - Aquatic toxicology, 2012 - Elsevier
Chlorophenols in the aquatic environment have been of concern due to their potential
effects on human and wildlife. In the present study, the endocrine disrupting effects of 2, 4 …

Effects of the UV-filter 2-ethyl-hexyl-4-trimethoxycinnamate (EHMC) on expression of genes involved in hormonal pathways in fathead minnows (Pimephales …

V Christen, S Zucchi, K Fent - Aquatic toxicology, 2011 - Elsevier
UV-filters are increasingly used in cosmetics and in the protection of materials against UV-
irradiation, and ultimately they reach aquatic systems. The lipophilic UV-filter 2-ethyl-hexyl-4 …

Transcriptional and Physiological Responses Induced by Binary Mixtures of Drospirenone and Progesterone in Zebrafish (Danio rerio)

S Zucchi, L Mirbahai, S Castiglioni… - Environmental science & …, 2014 - ACS Publications
Drospirenone (DRS) is a synthetic progestin increasingly used in oral contraceptives with
similar effects to progesterone (P4). Wild fish are exposed to DRS and P4 through …

The UV-absorber benzophenone-4 alters transcripts of genes involved in hormonal pathways in zebrafish (Danio rerio) eleuthero-embryos and adult males

S Zucchi, N Blüthgen, A Ieronimo, K Fent - Toxicology and Applied …, 2011 - Elsevier
Benzophenone-4 (BP-4) is frequently used as UV-absorber in cosmetics and materials
protection. Despite its frequent detection in the aquatic environment potential effects on …