This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical
oncology to treat solid tumors with irreversible electroporation (IRE) and …

Pulsed electrical field (PEF) energy is a promising technique for catheter ablation of cardiac
arrhythmias. In this article, the key aspects that need to be considered for safe and effective …

Common delivery routes for chemotherapeutics are based on circulation, which faces
clinical limitations to local delivery efficiency, and the conflict between the dose for …

Besides its broad application in research and biotechnology, genome editing (GE) has great
potential for clinical gene therapy, but delivery of GE tools remains a bottleneck. Whereas …

Electroporation is being successfully used in biology, medicine, food processing, and
biotechnology, and in some environmental applications. Recent applications also include in …

Atrial fibrillation is the most common sustained cardiac arrhythmia and is associated with
considerable morbidity and mortality. Electrically isolating the pulmonary veins from the left …

Background: Pulmonary vein isolation is a common catheter ablation technique used to treat
atrial fibrillation originating from the pulmonary veins. However, incomplete lesion formation …

Purpose: This study evaluates the effects of active electrode cooling, via internal fluid
circulation, on the irreversible electroporation (IRE) lesion, deployed electric current and …

Background. Irreversible electroporation (IRE) is a tissue ablation method, which relies on
the phenomenon of electroporation. When cells are exposed to a sufficiently electric field …

In this paper, we propose a new dynamical model of tissue electroporation. The model is
based on equivalent circuit approach at the tissue. Considering two current densities from …