The Huisgen reaction: milestones of the 1, 3‐dipolar cycloaddition

M Breugst, HU Reissig - Angewandte Chemie International …, 2020 - Wiley Online Library
Abstract The concept of 1, 3‐dipolar cycloadditions was presented by Rolf Huisgen 60 years
ago. Previously unknown reactive intermediates, for example azomethine ylides, were …

C–C bond cleavages of cyclopropenes: operating for selective ring-opening reactions

R Vicente - Chemical Reviews, 2020 - ACS Publications
This review highlights key reactivities relying on C–C bond cleavages of cyclopropenes.
Metal-catalyzed and metal-free transformations are covered in reactions involving direct ring …

Carbonyl–olefin metathesis

H Albright, AJ Davis, JL Gomez-Lopez… - Chemical …, 2021 - ACS Publications
This Review describes the development of strategies for carbonyl–olefin metathesis
reactions relying on stepwise, stoichiometric, or catalytic approaches. A comprehensive …

Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis

L Zhang, DA Nagib - Nature chemistry, 2024 - nature.com
Carbonyls and alkenes are versatile functional groups, whose reactivities are cornerstones
of organic synthesis. The selective combination of two carbonyls to form an alkene—a …

Carbonyl Olefin Metathesis and Dehydrogenative Cyclization of Aromatic Ketones and gem‐Difluoroalkenes

Y Zhang, J Wang, Y Guo, S Liu… - Angewandte Chemie …, 2024 - Wiley Online Library
The beauty of one‐pot cascade reaction lies in the efficient disconnection and construction
of several bonds in a single reaction flask, without the isolation of any intermediates. Herein …

Iron(III)-catalysed carbonyl–olefin metathesis

JR Ludwig, PM Zimmerman, JB Gianino, CS Schindler - Nature, 2016 - nature.com
The olefin metathesis reaction of two unsaturated substrates is one of the most powerful
carbon–carbon-bond-forming reactions in organic chemistry. Specifically, the catalytic olefin …

Catalytic isofunctional reactions—expanding the repertoire of shuttle and metathesis reactions

BN Bhawal, B Morandi - Angewandte Chemie International …, 2019 - Wiley Online Library
Transfer hydrogenation, alkene metathesis, and alkyne metathesis possess great value to
the synthetic chemistry community. One of the key features of these processes is their …

Polycyclic aromatic hydrocarbons via iron (iii)-catalyzed carbonyl–olefin metathesis

CC McAtee, PS Riehl, CS Schindler - Journal of the American …, 2017 - ACS Publications
Polycyclic aromatic hydrocarbons are important structural motifs in organic chemistry,
pharmaceutical chemistry, and materials science. The development of a new synthetic …

Beyond olefins: new metathesis directions for synthesis

MR Becker, RB Watson, CS Schindler - Chemical Society Reviews, 2018 - pubs.rsc.org
The olefin–olefin metathesis reaction has emerged as one of the most important carbon–
carbon bond-forming reactions, as illustrated by its wide use in the synthesis of complex …

Synthesis of 2 H-chromenes: recent advances and perspectives

SL Zheng, L Chen - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
As one type of chromene, 2H-chromenes represent important oxygen heterocycles, which
not only widely exist in natural products, pharmaceutical agents and biologically relevant …