[PDF][PDF] Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
Diffraction (X-ray, neutron and electron) and electron cryo-microscopy are powerful methods
to determine three-dimensional macromolecular structures, which are required to …
to determine three-dimensional macromolecular structures, which are required to …
[PDF][PDF] MolProbity: all-atom structure validation for macromolecular crystallography
VB Chen, WB Arendall, JJ Headd… - … Section D: Biological …, 2010 - journals.iucr.org
MolProbity is a structure-validation web service that provides broad-spectrum solidly based
evaluation of model quality at both the global and local levels for both proteins and nucleic …
evaluation of model quality at both the global and local levels for both proteins and nucleic …
Design of protein-binding proteins from the target structure alone
The design of proteins that bind to a specific site on the surface of a target protein using no
information other than the three-dimensional structure of the target remains a challenge …
information other than the three-dimensional structure of the target remains a challenge …
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
J Lan, J Ge, J Yu, S Shan, H Zhou, S Fan, Q Zhang… - nature, 2020 - nature.com
A new and highly pathogenic coronavirus (severe acute respiratory syndrome coronavirus-
2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from …
2, SARS-CoV-2) caused an outbreak in Wuhan city, Hubei province, China, starting from …
[HTML][HTML] Human neutralizing antibodies elicited by SARS-CoV-2 infection
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a global health emergency that …
respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a global health emergency that …
[HTML][HTML] Structural basis for potent neutralization of betacoronaviruses by single-domain camelid antibodies
Coronaviruses make use of a large envelope protein called spike (S) to engage host cell
receptors and catalyze membrane fusion. Because of the vital role that these S proteins play …
receptors and catalyze membrane fusion. Because of the vital role that these S proteins play …
Bacteriophages inhibit and evade cGAS-like immune function in bacteria
A fundamental strategy of eukaryotic antiviral immunity involves the cGAS enzyme, which
synthesizes 2′, 3′-cGAMP and activates the effector STING. Diverse bacteria contain …
synthesizes 2′, 3′-cGAMP and activates the effector STING. Diverse bacteria contain …
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
H Su, S Yao, W Zhao, M Li, J Liu, W Shang… - Acta Pharmacologica …, 2020 - nature.com
Human infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
causes coronavirus disease 2019 (COVID-19) and there is no cure currently. The 3CL …
causes coronavirus disease 2019 (COVID-19) and there is no cure currently. The 3CL …
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19
H Xu, S Li, J Liu, J Cheng, L Kang… - Proceedings of the …, 2023 - National Acad Sciences
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern,
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …
and effective antiviral reagents are urgently needed. Traditional Chinese medicine theory …
Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies
that circulate in blood plasma after severe acute respiratory syndrome coronavirus 2 (SARS …
that circulate in blood plasma after severe acute respiratory syndrome coronavirus 2 (SARS …