Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
[HTML][HTML] Antibody structure and function: the basis for engineering therapeutics
ML Chiu, DR Goulet, A Teplyakov, GL Gilliland - Antibodies, 2019 - mdpi.com
Antibodies and antibody-derived macromolecules have established themselves as the
mainstay in protein-based therapeutic molecules (biologics). Our knowledge of the structure …
mainstay in protein-based therapeutic molecules (biologics). Our knowledge of the structure …
Electrostatic interactions in protein structure, folding, binding, and condensation
Charged and polar groups, through forming ion pairs, hydrogen bonds, and other less
specific electrostatic interactions, impart important properties to proteins. Modulation of the …
specific electrostatic interactions, impart important properties to proteins. Modulation of the …
Improving peptide-protein docking with AlphaFold-Multimer using forced sampling
I Johansson-Åkhe, B Wallner - Frontiers in bioinformatics, 2022 - frontiersin.org
Protein interactions are key in vital biological processes. In many cases, particularly in
regulation, this interaction is between a protein and a shorter peptide fragment. Such …
regulation, this interaction is between a protein and a shorter peptide fragment. Such …
The structural basis of antibody-antigen recognition
I Sela-Culang, V Kunik, Y Ofran - Frontiers in immunology, 2013 - frontiersin.org
The function of antibodies (Abs) involves specific binding to antigens (Ags) and activation of
other components of the immune system to fight pathogens. The six hypervariable loops …
other components of the immune system to fight pathogens. The six hypervariable loops …
Hirshfeld surface analysis
MA Spackman, D Jayatilaka - CrystEngComm, 2009 - pubs.rsc.org
In the last few years the analysis of molecular crystal structures using tools based on
Hirshfeld surfaces has rapidly gained in popularity. This approach represents an attempt to …
Hirshfeld surfaces has rapidly gained in popularity. This approach represents an attempt to …
Anatomy of hot spots in protein interfaces
AA Bogan, KS Thorn - Journal of molecular biology, 1998 - Elsevier
Binding of one protein to another is involved in nearly all biological functions, yet the
principles governing the interaction of proteins are not fully understood. To analyze the …
principles governing the interaction of proteins are not fully understood. To analyze the …
How TCRs bind MHCs, peptides, and coreceptors
MG Rudolph, RL Stanfield, IA Wilson - Annu. Rev. Immunol., 2006 - annualreviews.org
Since the first crystal structure determinations of αβ T cell receptors (TCRs) bound to class I
MHC-peptide (pMHC) antigens in 1996, a sizable database of 24 class I and class II …
MHC-peptide (pMHC) antigens in 1996, a sizable database of 24 class I and class II …
Electrostatic potentials mapped on Hirshfeld surfaces provide direct insight into intermolecular interactions in crystals
MA Spackman, JJ McKinnon, D Jayatilaka - CrystEngComm, 2008 - pubs.rsc.org
Ab initio electrostatic potentials for molecules can readily be mapped onto their Hirshfeld
surfaces and displayed within a crystal packing diagram. In this manner the close molecular …
surfaces and displayed within a crystal packing diagram. In this manner the close molecular …
The Poisson–Boltzmann equation for biomolecular electrostatics: a tool for structural biology
F Fogolari, A Brigo, H Molinari - Journal of Molecular …, 2002 - Wiley Online Library
Electrostatics plays a fundamental role in virtually all processes involving biomolecules in
solution. The Poisson–Boltzmann equation constitutes one of the most fundamental …
solution. The Poisson–Boltzmann equation constitutes one of the most fundamental …
Close‐range electrostatic interactions in proteins
S Kumar, R Nussinov - ChemBioChem, 2002 - Wiley Online Library
Two types of noncovalent bonding interactions are present in protein structures, specific and
nonspecific. Nonspecific interactions are mostly hydrophobic and van der Waals. Specific …
nonspecific. Nonspecific interactions are mostly hydrophobic and van der Waals. Specific …