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Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula
L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …
systems biology theory, biological system network analysis, and multi-target drug molecule …
Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancer
S Li, W Yu, F ** tumor metabolic remodeling and their spatial crosstalk with surrounding non-tumor
cells can fundamentally improve our understanding of tumor biology, facilitates the …
cells can fundamentally improve our understanding of tumor biology, facilitates the …
Ex utero monkey embryogenesis from blastocyst to early organogenesis
Y Gong, B Bai, N Sun, B Ci, H Shao, T Zhang, H Yao… - Cell, 2023 - cell.com
The third and fourth weeks of gestation in primates are marked by several developmental
milestones, including gastrulation and the formation of organ primordia. However, our …
milestones, including gastrulation and the formation of organ primordia. However, our …
Loss of cold tolerance is conferred by absence of the WRKY34 promoter fragment during tomato evolution
M Guo, F Yang, L Zhu, L Wang, Z Li, Z Qi… - Nature …, 2024 - nature.com
Natural evolution has resulted in reduced cold tolerance in cultivated tomato (Solanum
lycopersicum). Herein, we perform a combined analysis of ATAC-Seq and RNA-Seq in cold …
lycopersicum). Herein, we perform a combined analysis of ATAC-Seq and RNA-Seq in cold …
Comparative RNA-seq analysis of tomato (Solanum lycopersicum L.) provides insights into natural and postharvest ripening
X Zhao, F Li, J Ding, X Fu, J Shang, X Kong, X Li… - Postharvest Biology and …, 2024 - Elsevier
Tomato is a popular fruit known for their delicious flavor and nutritional value. However,
there are significant differences in taste, nutritional content, and storage properties between …
there are significant differences in taste, nutritional content, and storage properties between …
Global genetic diversity, introgression, and evolutionary adaptation of indicine cattle revealed by whole genome sequencing
Indicine cattle, also referred to as zebu (Bos taurus indicus), play a central role in pastoral
communities across a wide range of agro-ecosystems, from extremely hot semiarid regions …
communities across a wide range of agro-ecosystems, from extremely hot semiarid regions …
Perturbation of METTL1-mediated tRNA N7- methylguanosine modification induces senescence and aging
Y Fu, F Jiang, X Zhang, Y Pan, R Xu, X Liang… - Nature …, 2024 - nature.com
Cellular senescence is characterized by a decrease in protein synthesis, although the
underlying processes are mostly unclear. Chemical modifications to transfer RNAs (tRNAs) …
underlying processes are mostly unclear. Chemical modifications to transfer RNAs (tRNAs) …
Astrocyte-derived lactate aggravates brain injury of ischemic stroke in mice by promoting the formation of protein lactylation
XY **ong, XR Pan, XX Luo, YF Wang, XX Zhang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Aim: Although lactate supplementation at the reperfusion stage of ischemic stroke has been
shown to offer neuroprotection, whether the role of accumulated lactate at the ischemia …
shown to offer neuroprotection, whether the role of accumulated lactate at the ischemia …
A transcription factor ZmGLK36 confers broad resistance to maize rough dwarf disease in cereal crops
Z Xu, Z Zhou, Z Cheng, Y Zhou, F Wang, M Li, G Li… - Nature Plants, 2023 - nature.com
Maize rough dwarf disease (MRDD), caused by maize rough dwarf virus (MRDV) or rice
black-streaked dwarf virus (RBSDV), seriously threatens worldwide production of all major …
black-streaked dwarf virus (RBSDV), seriously threatens worldwide production of all major …