Neonatal hypoxia ischaemia: mechanisms, models, and therapeutic challenges

LJ Millar, L Shi, A Hoerder-Suabedissen… - Frontiers in cellular …, 2017 - frontiersin.org
Neonatal hypoxia-ischaemia (HI) is the most common cause of death and disability in
human neonates, and is often associated with persistent motor, sensory, and cognitive …

Treatment advances in neonatal neuroprotection and neurointensive care

MV Johnston, A Fatemi, MA Wilson… - The Lancet …, 2011 - thelancet.com
Knowledge of the nature, prognosis, and ways to treat brain lesions in neonatal infants has
increased remarkably. Neonatal hypoxic-ischaemic encephalopathy (HIE) in term infants …

Mitochondrial oxidative stress and dysfunction in arsenic neurotoxicity: A review

C Prakash, M Soni, V Kumar - Journal of Applied Toxicology, 2016 - Wiley Online Library
Arsenic is a toxic metalloid present ubiquitously on earth. Since the last decade, it has
gained considerable attention due to its severe neurotoxic effects. Arsenic can cross the …

Hypothermia therapy for newborns with hypoxic ischemic encephalopathy

RC Silveira, RS Procianoy - Jornal de pediatria, 2015 - SciELO Brasil
Objective: Therapeutic hypothermia reduces cerebral injury and improves the neurological
outcome secondary to hypoxic ischemic encephalopathy in newborns. It has been indicated …

Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: recent developments

H Zhao, A Alam, CY San, S Eguchi, Q Chen, Q Lian… - Brain research, 2017 - Elsevier
Neuronal cell injury, as a consequence of acute or chronic neurological trauma, is a
significant cause of mortality around the world. On a molecular level, the condition is …

Biology of mitochondria in neurodegenerative diseases

LJ Martin - Progress in molecular biology and translational …, 2012 - Elsevier
Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS)
are the most common human adult-onset neurodegenerative diseases. They are …

[HTML][HTML] Mitochondrial and cell death mechanisms in neurodegenerative diseases

LJ Martin - Pharmaceuticals, 2010 - mdpi.com
Alzheimer's disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS)
are the most common human adult-onset neurodegenerative diseases. They are …

Melatonin protects from the long‐term consequences of a neonatal hypoxic‐ischemic brain injury in rats

S Carloni, S Perrone, G Buonocore… - Journal of pineal …, 2008 - Wiley Online Library
Among the main factors responsible for perinatal brain injury, inflammation, hypoxia‐
ischemia and formation of free radicals (FR) appear to play key roles. Melatonin, an …

Hypoxic‐ischemic‐related cerebrovascular changes and potential therapeutic strategies in the neonatal brain

C Disdier, BS Stonestreet - Journal of neuroscience research, 2020 - Wiley Online Library
Abstract Perinatal hypoxic‐ischemic (HI)‐related brain injury is an important cause of
morbidity and long‐standing disability in newborns. The only currently approved therapeutic …

Motor pathway injury in patients with periventricular leucomalacia and spastic diplegia

JD Lee, HJ Park, ES Park, MK Oh, B Park, DW Rha… - Brain, 2011 - academic.oup.com
Periventricular leucomalacia has long been investigated as a leading cause of motor and
cognitive dysfunction in patients with spastic diplegic cerebral palsy. However, patients with …