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Advanced 3D models of human brain tissue using neural cell lines: state-of-the-art and future prospects
R Fabbri, L Cacopardo, A Ahluwalia, C Magliaro - Cells, 2023 - mdpi.com
Human-relevant three-dimensional (3D) models of cerebral tissue can be invaluable tools to
boost our understanding of the cellular mechanisms underlying brain pathophysiology …
boost our understanding of the cellular mechanisms underlying brain pathophysiology …
Nano-architectural approaches for improved intracortical interface technologies
Intracortical microelectrodes (IME) are neural devices that initially were designed to function
as neuroscience tools to enable researchers to understand the nervous system. Over the …
as neuroscience tools to enable researchers to understand the nervous system. Over the …
[HTML][HTML] Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells
A Chandrasekaran, HX Avci, A Ochalek, LN Rösingh… - Stem cell …, 2017 - Elsevier
Neural progenitor cells (NPCs) from human induced pluripotent stem cells (hiPSCs) are
frequently induced using 3D culture methodologies however, it is unknown whether …
frequently induced using 3D culture methodologies however, it is unknown whether …
Rheology and direct write printing of chitosan-graphene oxide nanocomposite hydrogels for differentiation of neuroblastoma cells
SG Marapureddy, P Hivare, A Sharma… - Carbohydrate …, 2021 - Elsevier
The direct write printing method has gained popularity in synthesizing scaffolds for tissue
engineering. To achieve an excellent printability of scaffolds, a thorough evaluation of …
engineering. To achieve an excellent printability of scaffolds, a thorough evaluation of …
Microenvironments matter: advances in brain-on-chip
G Akcay, R Luttge - Biosensors, 2023 - mdpi.com
To highlight the particular needs with respect to modeling the unique and complex
organization of the human brain structure, we reviewed the state-of-the-art in devising brain …
organization of the human brain structure, we reviewed the state-of-the-art in devising brain …
The need for physiological micro-nanofluidic systems of the brain
In this article, we review brain-on-a-chip models and associated underlying technologies.
Micro-nanofluidic systems of the brain can utilize the entire spectrum of organoid …
Micro-nanofluidic systems of the brain can utilize the entire spectrum of organoid …
Generating CNS organoids from human induced pluripotent stem cells for modeling neurological disorders
AT Brawner, R Xu, D Liu… - International Journal of …, 2017 - pmc.ncbi.nlm.nih.gov
Understanding human brain development and disease is largely hampered by the relative
inaccessibility of human brain tissues. Recent advances in human induced pluripotent stem …
inaccessibility of human brain tissues. Recent advances in human induced pluripotent stem …
Nanocellulose-collagen composites as advanced biomaterials for 3D in-vitro neuronal model systems
V Torresan, LM Dedroog, O Deschaume, E Koos… - Carbohydrate …, 2025 - Elsevier
Studying brain diseases and develo** therapies requires versatile in vitro systems for long-
term neuronal cultures. SH-SY5Y neuroblastoma cells are ideal for modeling …
term neuronal cultures. SH-SY5Y neuroblastoma cells are ideal for modeling …
Advancing a MEMS-Based 3D Cell Culture System for in vitro Neuro-Electrophysiological Recordings
AJ Bastiaens, JP Frimat, T van Nunen… - Frontiers in …, 2018 - frontiersin.org
In this work we present advances in three dimensional (3D) neuronal cell culture systems
based on a reversible assembly of a microbioreactor with a microelectrode array (MEA) to …
based on a reversible assembly of a microbioreactor with a microelectrode array (MEA) to …
[HTML][HTML] Nanogroove-enhanced hydrogel scaffolds for 3D neuronal cell culture: An easy access brain-on-chip model
A Bastiaens, S **e, R Luttge - Micromachines, 2019 - mdpi.com
In order to better understand the brain and brain diseases, in vitro human brain models need
to include not only a chemically and physically relevant microenvironment, but also …
to include not only a chemically and physically relevant microenvironment, but also …