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COVID-19: Discovery, diagnostics and drug development
Summary Coronavirus disease 2019 (COVID-19) started as an epidemic in Wuhan in 2019,
and has since become a pandemic. Groups from China identified and sequenced the virus …
and has since become a pandemic. Groups from China identified and sequenced the virus …
COVID-19 and liver dysfunction: current insights and emergent therapeutic strategies
The outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has attracted increasing worldwide …
respiratory syndrome coronavirus 2 (SARS-CoV-2), has attracted increasing worldwide …
Precision navigation of hepatic ischemia–reperfusion injury guided by lysosomal viscosity-activatable NIR-II fluorescence
J Liu, W Zhang, C Zhou, M Li, X Wang… - Journal of the …, 2022 - ACS Publications
Hepatic ischemia–reperfusion injury (HIRI) is responsible for postoperative liver dysfunction
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …
and liver failure. Precise and rapid navigation of HIRI lesions is critical for early warning and …
Viscosity-responsive NIR-II fluorescent probe with aggregation-induced emission features for early diagnosis of liver injury
J Ge, W Cai, N Niu, Y Wen, Q Wu, L Wang, D Wang… - Biomaterials, 2023 - Elsevier
As the primary organ for drug metabolism and detoxification, the liver is susceptible to
damage and seriously impaired function. In situ diagnosing and real-time monitoring of liver …
damage and seriously impaired function. In situ diagnosing and real-time monitoring of liver …
Dynamic–reversible MRI nanoprobe for continuous imaging redox homeostasis in hepatic ischemia–reperfusion injury
C Zhang, L Xu, B Nan, C Lu, H Liu, L Lei, R Yue… - ACS …, 2023 - ACS Publications
Hepatic ischemia–reperfusion (I/R) injury accompanied by oxidative stress is responsible for
postoperative liver dysfunction and failure of liver surgery. However, the dynamic non …
postoperative liver dysfunction and failure of liver surgery. However, the dynamic non …
Incidence, risk factors, and prognosis of abnormal liver biochemical tests in COVID-19 patients: a systematic review and meta-analysis
Y Wu, H Li, X Guo, EM Yoshida… - Hepatology …, 2020 - Springer
Background and aims Coronavirus disease 2019 (COVID-19) pandemic is ongoing. Except
for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted …
for lung injury, it is possible that COVID-19 patients develop liver injury. Thus, we conducted …
TRPM2 Mediates Hepatic Ischemia–Reperfusion Injury via Ca2+-Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression
C Zhong, J Yang, Y Zhang, X Fan, Y Fan, N Hua, D Li… - Research, 2023 - spj.science.org
Hepatic ischemia–reperfusion (IR) injury is a serious clinical problem that complicates liver
resection and transplantation. Despite recent advances in understanding of the …
resection and transplantation. Despite recent advances in understanding of the …
Insights into the epidemiology, pathogenesis, and therapeutics of nonalcoholic fatty liver diseases
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease which affects≈
25% of the adult population worldwide, placing a tremendous burden on human health. The …
25% of the adult population worldwide, placing a tremendous burden on human health. The …
The role of mitochondria in liver ischemia‐reperfusion injury: from aspects of mitochondrial oxidative stress, mitochondrial fission, mitochondrial membrane permeable …
H Zhang, Q Yan, X Wang, X Chen… - Oxidative medicine …, 2021 - Wiley Online Library
Ischemia‐reperfusion injury (IRI) has indeed been shown as a main complication of
hepatectomy, liver transplantation, trauma, and hypovolemic shock. A large number of …
hepatectomy, liver transplantation, trauma, and hypovolemic shock. A large number of …
Hepatic consequences of COVID-19 infection. Lap** or biting?
P Portincasa, M Krawczyk, A Machill, F Lammert… - European journal of …, 2020 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) starting last December in China
placed emphasis on liver involvement during infection. This review discusses the underlying …
placed emphasis on liver involvement during infection. This review discusses the underlying …