Neutralization of Bitis arietans venom-induced pathophysiological disorder, biological activities and genetic alterations by Moringa oleifera leaves

BS Ajisebiola, S Rotimi, U Anwar, AO Adeyi - Toxin reviews, 2021 - Taylor & Francis
Bitis arietans venom (BAV) is known to cause various pathophysiological disorders by
altering the cellular inclusions and enzymatic activities of different organs. Moringa oleifera …

Kaempferol from Moringa oleifera demonstrated potent antivenom activities via inhibition of metalloproteinase and attenuation of Bitis arietans venom–induced …

BS Ajisebiola, JO Oladele, AO Adeyi - Toxicon, 2023 - Elsevier
Bitis arietans venom (BAV) can induce severe pathophysiological disorders after
envenoming. However, studies have shown that the Moringa oleifera fraction is effective …

Kaempferol mitigates reproductive dysfunctions induced by Naja nigricollis venom through antioxidant system and anti-inflammatory response in male rats

AO Adeyi, BS Ajisebiola, AA Sanni, JO Oladele… - Scientific Reports, 2024 - nature.com
Abstract Naja nigricollis Venom (NnV) contains complex toxins that affects various vital
systems functions after envenoming. The venom toxins have been reported to induce male …

Preclinical efficacy of African medicinal plants used in the treatment of snakebite envenoming: a systematic review protocol

AA Bala, M Mohammed, S Umar… - Therapeutic …, 2022 - journals.sagepub.com
Background: Snakebite envenoming (SBE) is a high-priority, neglected, tropical disease that
affects millions of people in develo** countries annually. The only available standard drug …

[HTML][HTML] Naja nigricollis venom altered reproductive and neurological functions via modulation of pro-inflammatory cytokines and oxidative damage in male rats

BS Ajisebiola, OB Adeniji, AS James, BO Ajayi… - Metabolism Open, 2022 - Elsevier
Reproductive and neurological anomalies are often characterized by malfunctioning of
reproductive and nervous organs sometimes attributed to systemic toxins. However, limited …

[HTML][HTML] Moringa oleifera leaf fractions attenuated Naje haje venom-induced cellular dysfunctions via modulation of Nrf2 and inflammatory signalling pathways in rats

AO Adeyi, BS Ajisebiola, OE Adeyi, O Adekunle… - … and biophysics reports, 2021 - Elsevier
Naja haje envenoming could activate multiple pathways linked to haematotoxic,
neurological, and antioxidant systems dysfunctions. Moringa oleifera has been used in the …

Inhibition of Metalloproteinase from Bitis arietans Venom In Vitro by the Ethyl Acetate Fraction of Moringa oleifera and Its Chemical Profile

BS Ajisebiola, FT Bello, PM Osamudiamen… - Revista Brasileira de …, 2023 - Springer
Abstract Moringa oleifera Lam., Moringaceae, ethyl acetate soluble fraction has been
documented to contain bioactive antivenom chemicals against Bitis arietans venom …

Detoxifying action of aqueous extracts of Mucuna pruriens seed and Mimosa pudica root against venoms of Naja nigricollis and Bitis arietans

MP Ameh, M Mohammed, YP Ofemile… - Recent Patents on …, 2020 - ingentaconnect.com
Background: The World Health Organization included snakebite envenomation among
Neglected Tropical Diseases in 2017. The importance of natural products from plants is …

Knowledge assessment of snake antivenom among healthcare practitioners involving educational intervention in northern Nigeria: a study protocol

AA Bala, AI Jatau, I Yunusa… - … advances in drug …, 2020 - journals.sagepub.com
Introduction Snakebite envenoming (SBE) is an important occupational and public health
hazard especially in sub-Saharan Africa. For optimum management of SBE, adequate …

Knowledge assessment of anti-snake venom among healthcare practitioners in northern Nigeria

AA Bala, AI Jatau, I Yunusa… - Therapeutic …, 2021 - journals.sagepub.com
Introduction: Anti-snake venom (ASV) is the standard therapy for the management of
snakebite envenoming (SBE). Therefore, the knowledge of ASV among healthcare …