Spontaneous intracerebral hemorrhage

KN Sheth - New England Journal of Medicine, 2022 - Mass Medical Soc
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Intracerebral haemorrhage

L Puy, AR Parry-Jones, EC Sandset… - Nature Reviews …, 2023 - nature.com
Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral
vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke …

Cerebral hemorrhage: pathophysiology, treatment, and future directions

J Magid-Bernstein, R Girard, S Polster… - Circulation …, 2022 - Am Heart Assoc
Intracerebral hemorrhage (ICH) is a devastating form of stroke with high morbidity and
mortality. This review article focuses on the epidemiology, cause, mechanisms of injury …

Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage

SJ Connolly, M Sharma, AT Cohen… - … England Journal of …, 2024 - Mass Medical Soc
Background Patients with acute intracerebral hemorrhage who are receiving factor Xa
inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that …

[HTML][HTML] Hypertension and stroke: update on treatment

M Wajngarten, GS Silva - European Cardiology Review, 2019 - ncbi.nlm.nih.gov
Stroke is the second most common cause of mortality worldwide and the third most common
cause of disability. Hypertension is the most prevalent risk factor for stroke. Stroke causes …

Surgery for spontaneous intracerebral hemorrhage

AL de Oliveira Manoel - Critical Care, 2020 - Springer
Spontaneous intracerebral hemorrhage is a devastating disease, accounting for 10 to 15%
of all types of stroke; however, it is associated with disproportionally higher rates of mortality …

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial

N Sprigg, K Flaherty, JP Appleton, RAS Salman… - The Lancet, 2018 - thelancet.com
Background Tranexamic acid can prevent death due to bleeding after trauma and post-
partum haemorrhage. We aimed to assess whether tranexamic acid reduces haematoma …

Treatment and outcome of hemorrhagic transformation after intravenous alteplase in acute ischemic stroke: a scientific statement for healthcare professionals from the …

S Yaghi, JZ Willey, B Cucchiara, JN Goldstein… - Stroke, 2017 - Am Heart Assoc
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

[HTML][HTML] Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data

RAS Salman, J Frantzias, RJ Lee, PD Lyden… - The Lancet …, 2018 - thelancet.com
Background Intracerebral haemorrhage growth is associated with poor clinical outcome and
is a therapeutic target for improving outcome. We aimed to determine the absolute risk and …

Role and mechanisms of cytokines in the secondary brain injury after intracerebral hemorrhage

H Zhu, Z Wang, J Yu, X Yang, F He, Z Liu, F Che… - Progress in …, 2019 - Elsevier
Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …