[HTML][HTML] Protective effects of diets rich in polyphenols in cigarette smoke (CS)-induced oxidative damages and associated health implications

M Rudrapal, S Maji, SK Prajapati, P Kesharwani… - Antioxidants, 2022 - mdpi.com
Cigarette smoking has been responsible for causing many life-threatening diseases such as
pulmonary and cardiovascular diseases as well as lung cancer. One of the prominent health …

[HTML][HTML] Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: In vitro and in vivo studies

M Yasser, EE El Naggar, N Elfar, MH Teaima… - International Journal of …, 2024 - Elsevier
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the
Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for …

A whole-course-repair system based on ROS/glucose stimuli-responsive EGCG release and tunable mechanical property for efficient treatment of chronic periodontitis …

Q Feng, M Zhang, G Zhang, H Mei, C Su… - Journal of Materials …, 2024 - pubs.rsc.org
Elevated glucose levels, multiple pro-inflammatory cytokines and the generation of
excessive reactive oxygen species (ROS) are pivotal characteristics within the …

Spanlastics: a novel elastic drug delivery system with potential applications via multifarious routes of administration

H Saini, Y Rapolu, K Razdan, Nirmala… - Journal of Drug …, 2023 - Taylor & Francis
Drug delivery systems (DDS) based on nanocarriers are designed to transport therapeutic
agents to specific areas of the body where they are required to exhibit pharmacodynamic …

Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in …

NAN Hanafy, RH Abdelbadea, AE Abdelaziz… - Cancer …, 2023 - Springer
This study aimed to overcome the poor solubility of pterostilbene (PTS) by develo**
promising reconstituted proethoniosomes (PENs). The reconstituted PENs loaded with PTS …

Spanlastics as an efficient delivery system for the enhancement of thymoquinone anticancer efficacy: Fabrication and cytotoxic studies against breast cancer cell lines

E Alaaeldin, M Mostafa, HF Mansour… - Journal of Drug Delivery …, 2021 - Elsevier
Thymoquinone (TQ), a pleiotropic compound isolated from the seeds of Nigella sativa has a
great potential as a chemotherapeutic agent against several cancers. However, its limited …

[HTML][HTML] Spanlastic-laden nanogel as a plausible platform for dermal delivery of bimatoprost with superior cutaneous deposition and hair regrowth efficiency in …

BK Almutairy, ES Khafagy, MF Aldawsari… - International Journal of …, 2024 - Elsevier
Bimatoprost (BIM) is a prostaglandin F2α analogs originally approved for the treatment of
glaucoma and ocular hypertension. Recent studies have highlighted its potential to boost …

Glycerospanlastics: State-of-the-art two-in-one nano-vesicles for boosting ear drug delivery in otitis media treatment

M Magdy, E Elmowafy, M Elassal, RAH Ishak - International Journal of …, 2023 - Elsevier
The purpose of this research was to design innovative nanovesicles for ototopical
conveyance of triamcinolone acetonide (TA) for otitis media (OM) treatment via incorporating …

Spanlastic nanovesicles for enhanced ocular delivery of vanillic acid: Design, in vitro characterization, and in vivo anti-inflammatory evaluation

SS Ibrahim, H Abd-Allah - International Journal of Pharmaceutics, 2022 - Elsevier
Spanlastics are novel surfactant-based, elastic vesicular nanocarriers composed of spans
and edge activators. The present work aims to exploit their special penetration enhancing …

Fabrication and optimization of raloxifene loaded spanlastics vesicle for transdermal delivery

MD Ansari, P Solanki, J Pandit, RN Jahan… - Journal of Drug Delivery …, 2022 - Elsevier
This research work is envisioned for the development and optimization of Raloxifene HCL
loaded spanlastics. Raloxifene HCL, a selective estrogen receptor modulator (SERM), is …