Current state and challenges in develo** oral vaccines
While vaccination remains the most cost effective strategy for disease prevention,
communicable diseases persist as the second leading cause of death worldwide. There is a …
communicable diseases persist as the second leading cause of death worldwide. There is a …
An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers
Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …
effectiveness, ease of administration, and high patient compliance. However, the absorption …
Role of nanoparticle size, shape and surface chemistry in oral drug delivery
A Banerjee, J Qi, R Gogoi, J Wong… - Journal of Controlled …, 2016 - Elsevier
Nanoparticles find intriguing applications in oral drug delivery since they present a large
surface area for interactions with the gastrointestinal tract and can be modified in various …
surface area for interactions with the gastrointestinal tract and can be modified in various …
[HTML][HTML] Multi-endpoint toxicological assessment of polystyrene nano-and microparticles in different biological models in vitro
M Hesler, L Aengenheister, B Ellinger, R Drexel… - Toxicology in Vitro, 2019 - Elsevier
Nanoplastics (NP) and microplastics (MP) accumulate in our environment as a consequence
of the massive consumption of plastics. Huge knowledge-gaps exist regarding uptake and …
of the massive consumption of plastics. Huge knowledge-gaps exist regarding uptake and …
[HTML][HTML] Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
P Lundquist, P Artursson - Advanced drug delivery reviews, 2016 - Elsevier
In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …
Nanoparticles for oral delivery: Design, evaluation and state-of-the-art
The oral route is a preferred method of drug administration, though achieving effective drug
delivery and minimizing off-target side effects is often challenging. Formulation into …
delivery and minimizing off-target side effects is often challenging. Formulation into …
Advances in nutraceutical delivery systems: From formulation design for bioavailability enhancement to efficacy and safety evaluation
RFS Gonçalves, JT Martins, CMM Duarte… - Trends in Food Science …, 2018 - Elsevier
Background Aiming at the enhancement of food products' nutritional and health value, the
incorporation of nutraceuticals has attracted increasing interest in the last years. However …
incorporation of nutraceuticals has attracted increasing interest in the last years. However …
Distinct accumulation of nanoplastics in human intestinal organoids
Plastic particles, especially nanoplastics, represent an emerging concern of threat to human
health, oral uptake is an important pathway for the plastic particles ingestion by human …
health, oral uptake is an important pathway for the plastic particles ingestion by human …
Solid lipid nanoparticles for enhanced oral absorption: A review
E Salah, MM Abouelfetouh, Y Pan, D Chen… - colloids and surfaces B …, 2020 - Elsevier
Recent trends in nanoparticles-based oral therapy have led to a proliferation of studies to
enhance solubility, permeability and chemical stability of many drugs. One of the significant …
enhance solubility, permeability and chemical stability of many drugs. One of the significant …
[HTML][HTML] Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine
V Francia, D Montizaan… - Beilstein journal of …, 2020 - beilstein-journals.org
Nano-sized materials have great potential as drug carriers for nanomedicine applications.
Thanks to their size, they can exploit the cellular machinery to enter cells and be trafficked …
Thanks to their size, they can exploit the cellular machinery to enter cells and be trafficked …