Here, we provide an update of our review on homeobox genes that we wrote together with
Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have …

▪ Abstract Over 35 years ago, Susumu Ohno stated that gene duplication was the single
most important factor in evolution. He reiterated this point a few years later in proposing that …

Molluscs comprise the second largest phylum of animals (after arthropods), occurring in
virtually all habitats. Some are commercially important, a few are pests and some carry …

Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat,
owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences …

Many homeobox genes encode transcription factors with regulatory roles in animal and
plant development. Homeobox genes are found in almost all eukaryotes, and have …

Background The homeobox genes are a large and diverse group of genes, many of which
play important roles in the embryonic development of animals. Increasingly, homeobox …

▪ Abstract Endoderm, one of the three principal germ layers, contributes to all organs of the
alimentary tract. For simplicity, this review divides formation of endodermal organs into four …

Once called the'Rosetta stone'of developmental biology, the homeobox continues to
fascinate both evolutionary and developmental biologists. The birth of the homeotic, or Hox …

HOXA9 is a homeodomain-containing transcription factor that has an important role in
hematopoietic stem cell expansion and is commonly deregulated in acute leukemias. A …

Hox genes encode homeodomain-containing transcription factors that pattern the body axes
of animal embryos. It is well established that the exquisite DNA-binding specificity that …