[HTML][HTML] Decoding the Role of O-GlcNAcylation in Hepatocellular Carcinoma

X Zhou, S Hang, Q Wang, L Xu, P Wang - Biomolecules, 2024 - mdpi.com
Post-translational modifications (PTMs) influence protein functionality by modulating protein
stability, localization, and interactions with other molecules, thereby controlling various …

[HTML][HTML] Guarding against digestive-system cancers: Unveiling the role of Chk2 as a potential therapeutic target

Y An, D Gao, Y He, N Ge, J Guo, S Sun, C Wang… - Genes & …, 2025 - Elsevier
Digestive-system cancers represent major threats to human health; however, the
mechanisms underlying tumorigenesis and radiochemotherapy resistance have remained …

SLC50A1 inhibits the doxorubicin sensitivity in hepatocellular carcinoma cells through regulating the tumor glycolysis

G Wang, W **, L Zhang, M Dong, X Zhang… - Cell Death …, 2024 - nature.com
Metabolic reprogramming has been found to be closely associated with the occurrence and
development of hepatocellular carcinoma (HCC). The relationship between SLC50A1, a …

Identification of hepatocellular carcinoma-related subtypes and development of a prognostic model: a study based on ferritinophagy-related genes

G Wang, J Li, L Zhu, Z Zhou, Z Ma, H Zhang, Y Yang… - Discover Oncology, 2023 - Springer
Background Hepatocellular carcinoma still has a high incidence and mortality rate
worldwide, and further research is needed to investigate its occurrence and development …

Lnc-SNHG5 Promoted Hepatocellular Carcinoma Progression Through the RPS3-NFκB Pathway

J Hao, Y Liu, F Guo, G Fu, J Ning, X Ruan… - … Journal of General …, 2023 - Taylor & Francis
Background We planned to explore the underlying mechanism and clinical significance of
lnc-SNHG5 and RPS3 in hepatocellular carcinoma in this current study. Methods The …

c-Rel drives pancreatic cancer metastasis through Fibronectin-Integrin signaling-induced isolation stress resistance and EMT activation

D Bakırdöğen, K Görgülü, J **n, S Alcalá… - bioRxiv, 2025 - biorxiv.org
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies, with
limited treatment options and a high recurrence rate. Recurrence happens often with …

Identification of genes conferring individual-level variation responsible for metabolic dysfunction-associated steatohepatitis using single-cell eQTL analysis

SE Hong, SJ Mun, YJ Lee, T Yoo, KS Suh, KW Kang… - bioRxiv, 2024 - biorxiv.org
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized
for its medical and socioeconomic impacts, driven by diverse genetic and environmental …