The interest in therapeutic cancer vaccines has caught enormous attention in recent years
due to several breakthroughs in cancer research, among which the finding that successful …

mRNA vaccines have evolved as promising cancer therapies. These vaccines can encode
tumor-allied antigens, thus enabling personalized treatment approaches. They can also …

This extensive review summarizes clinical evidence on immunotherapy and targeted
therapy currently available for endometrial cancer (EC) and reports the results of the clinical …

Over the last two decades, dendritic cell (DC) vaccination has been studied extensively as
active immunotherapy in cancer treatment and has been proven safe in all clinical trials both …

Tumor immunotherapy has attracted more and more attention nowadays, and multiple
clinical trials have confirmed its effect in a variety of solid tumors. Immune checkpoint …

Lymph node (LN) macrophages play critical roles in anti‐tumor immunity, which develops
via the activation of cytotoxic T cells (CTL) and NK cells. The present study aims to …

Increasing demand for large-scale synthesis of in vitro transcribed (IVT) mRNA is being
driven by the increasing use of mRNA for transient gene expression in cell engineering and …

Simple Summary Gynecological cancers represent a group of malignancies with high
incidence and mortality, despite their relative sensitivity to platinum-based chemotherapy …

In recent years, the interest in using messenger RNA (mRNA) as a therapeutic means to
tackle different diseases has enormously increased. This holds true not only for numerous …

The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …